Results 51 to 60 of about 331,196 (308)

A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2015
Tyramine sulfamate was linked to the trityl chloride resin and this polymeric support used to introduce two levels of molecular diversity by formation of peptide bonds. A dual cleavage strategy next generated in a sequential way (without resin split) two
Diane Fournier, Liviu Ciobanu, Donald Poirier   +2 more
doaj  

Convenient methods for preparing π-conjugated linkers as building blocks for modular chemistry

Beilstein Journal of Organic Chemistry, 2009
Simple, straightforward and optimized procedures for preparing extended π-conjugated linkers are described. Either unsubstituted or 4-donor substituted π-linkers bearing a styryl, biphenyl, phenylethenylphenyl, and phenylethynylphenyl π-conjugated ...
Jiří Kulhánek, Filip Bureš, Miroslav Ludwig   +2 more
doaj   +1 more source

Linker-Compensated MetalOrganic Framework with Electron Delocalized Metal Sites for Bifunctional Oxygen Electrocatalysis

, 2022
Metal–organic frameworks with tailorable coordination chemistry are propitious for regulating catalytic performance and deciphering genuine mechanisms. Herein, a linker compensation strategy is proposed to alter the intermediate adsorption free energy on
Zhongwei Chen, Ning Chen (127610), Ya-Ping Deng, Ruilin Liang, Graham King (1682941), Yi Jiang (40197), Zhongwei Chen (309700), Ruilin Liang (4568782), Ning Chen, Ya-Ping Deng (3335901), Graham King, Aiping Yu (1418857), Aiping Yu, Yi Jiang   +13 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Improved Cross-Linking Coverage for Protein Complexes Containing Low Levels of Lysine by Using an Enrichable Photo-Cross-Linker

, 2023
Chemical cross-linking coupled with mass spectrometry (XL-MS) is an important technique for the structural analysis of protein complexes where the coverage of amino acids and the identification of cross-linked sites are crucial.
Zhigang Sui, Zhigang Sui (1911073), Lihua Zhang (22614), Zhou Gong, Lili Zhao, Beirong Zhang, Hang Gao, Qun Zhao, Zhen Liang, Yukui Zhang, Zhou Gong (135082), Zhen Liang (659089), Bowen Zhong, Lihua Zhang, Lili Zhao (442802), Qun Zhao (603175), Yukui Zhang (1413592), Hang Gao (1457464), Bowen Zhong (7386536), Beirong Zhang (12551182)   +19 more
core   +2 more sources

Selective ring-opening metathesis polymerization (ROMP) of cyclobutenes. Unsymmetrical ladderphane containing polycyclobutene and polynorbornene strands

Beilstein Journal of Organic Chemistry, 2019
At 0 °C in THF in the presence of Grubbs first generation catalyst, cyclobutene derivatives undergo ROMP readily, whereas norbornene derivatives remain intact. When the substrate contains both cyclobutene and norbornene moieties, the conditions using THF
Yuan-Zhen Ke, Shou-Ling Huang, Guoqiao Lai, Tien-Yau Luh   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The Construction of Immunoliposomes (Review)

Разработка и регистрация лекарственных средств, 2022
Introduction. Due to the discovery of antibodies (Ab) targeting molecule with high specificity to the ligand, the "magic bullet" concept has been successfully implemented with various immunoconjugated drugs. Since 1980, Ab conjugates with liposomes, i.e.,
M. V. Dmitrieva, I. V. Yarosh, E. V. Sanarova, A. V. Lantsova, O. L. Orlova   +4 more
doaj   +1 more source

ATP-dependent chromatosome remodeling [PDF]

, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Chioda, Mariacristina, Becker, Peter B., Maier, Verena K.   +2 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source