Results 41 to 50 of about 331,196 (308)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

OmDet: Large‐scale vision‐language multi‐dataset pre‐training with multimodal detection network

IET Computer Vision
The advancement of object detection (OD) in open‐vocabulary and open‐world scenarios is a critical challenge in computer vision. OmDet, a novel language‐aware object detection architecture and an innovative training mechanism that harnesses continual ...
Tiancheng Zhao, Peng Liu, Kyusong Lee
doaj   +1 more source

Antibody–Drug Conjugates: The Last Decade

Pharmaceuticals, 2020
An armed antibody (antibody–drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm.
Nicolas Joubert, Alain Beck, Charles Dumontet, Caroline Denevault-Sabourin   +3 more
doaj   +1 more source

Linker-Regulated H₂S Release from Aromatic Peptide Amphiphile Hydrogels

, 2020
Controlled release is an essential requirement for delivery of hydrogen sulfide (H2S) because of its reactive nature, short half-life in biological fluids, and toxicity at high concentrations.
Kuljeet Kaur, John B. Matson (1443253), Yin Wang, Yin Wang (34938), Kuljeet Kaur (285172), John B. Matson   +5 more
core   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Synthesis of “Porphyrin-Linker-Thiol” Molecules with Diverse Linkers for Studies of Molecular-Based Information Storage

, 2016
The attachment of redox-active molecules such as porphyrins to an electroactive surface provides an attractive approach for electrically addressable molecular-based information storage. Porphyrins are readily attached to a gold surface via thiol linkers.
Narasaiah Dontha (3025554), Werner G. Kuhr (2942787), David F. Bocian (1417588), Daniel T. Gryko (1357227), Christian Clausen (2956758), Jonathan S. Lindsey (1581841), Kristian M. Roth (2988765)   +6 more
core   +2 more sources

Optimal number of linkers per monomer in linker-mediated aggregation [PDF]

Soft Matter, 2019
We study the dynamics of diffusion-limited irreversible aggregation of monomers, where bonds are mediated by linkers.
G. C. Antunes, C. S. Dias, M. M. Telo da Gama, N. A. M. Araújo   +3 more
openaire   +3 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Anti-Fungal Hevein-like Peptides Biosynthesized from Quinoa Cleavable Hololectins

Molecules, 2021
Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally synthesized peptides that are known to be bioprocessed from the following
Shining Loo, Stephanie V. Tay, Antony Kam, Fan Tang, Jing-Song Fan, Daiwen Yang, James P. Tam   +6 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source