Results 101 to 110 of about 2,865,343 (269)
Linking Error Estimation in Stocking–Lord Linking
FoundationsStocking–Lord (SL) linking is a widely used linking method based on item response theory (IRT). This article examines the variability in SL linking parameter estimates within the two-parameter logistic (2PL) model.
Alexander Robitzsch
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Privacy Illusion: Subliminal Channels in Schnorr-like Blind-Signature Schemes
Applied SciencesBlind signatures are one of the key techniques of Privacy-Enhancing Technologies (PETs). They appear as a component of many schemes, including, in particular, the Privacy Pass technology.
Mirosław Kutyłowski, Oliwer Sobolewski
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Implementation Aspects in Simulation Extrapolation-Based Stocking–Lord Linking
Applied SciencesStocking–Lord (SL) linking is commonly used for group comparisons based on dichotomous item responses. Recently, the simulation extrapolation (SIMEX) method for SL linking has been introduced within the two-parameter logistic (2PL) model to reduce the ...
Alexander Robitzsch
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Studies in Chinese LinguisticsThe morpheme po55 in the Yanzhou (Jiande) dialect functions as either a verb of giving or an object marker (Cao 2017). In the former case, po55 patterns with the ditransitive verb gěi in Mandarin Chinese, where the mode of transfer is semantically ...
Wang Vincent Ji-Xin, Yuan Hua-Hung
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FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source