Results 111 to 120 of about 1,400,039 (300)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Linking Decisions with Moments [PDF]

open access: yes
This paper proposes a mechanism that can be operated without money in situations where agents have to decide over some common projects when they are not informed about others' preferences.
Róbert Veszteg
core  

High-Curie-Temperature Elastic Polymer Ferroelectric by Carbene Cross-Linking

open access: yes
With the emergence of wearable electronics, ferroelectrics are poised to serve as key components for numerous potential applications. Currently, intrinsically elastic ferroelectrics featuring a network structure through a precise “slight cross-linking ...
Run-Wei Li (1571662)   +8 more
core   +2 more sources

Estimation of Standard Error, Linking Error, and Total Error for Robust and Nonrobust Linking Methods in the Two-Parameter Logistic Model

open access: yesStats
The two-parameter logistic (2PL) item response theory model is a statistical model for analyzing multivariate binary data. In this article, two groups are brought onto a common metric using the 2PL model using linking methods. The linking methods of mean–
Alexander Robitzsch
doaj   +1 more source

Linking results of key and supplementary comparisons of regional metrology organization for electrical power

open access: yesInternational Journal of Metrology and Quality Engineering, 2016
A regional key comparison EURAMET.EM-K5.1 and a supplementary comparison COOMET. EM-S2 for electrical power were conducted between participating laboratories from the Eurasian region.
Velychko Oleh, Karpenko Stanislav
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Cross-linking del collagene corneale e biomeccanica delle cornee

open access: yes, 2012
L'obiettivo principale del progetto consiste nell'ultilizzare il cross-linking del collagene corneale per un uovo approccio alle patologie che provocano una ridotta resitenza biomeccanica della cornea.Una varietà di condizioni primarie, quali ...
SACCHI, ANTONIA
core  

Comparing Robust Haberman Linking and Invariance Alignment

open access: yesStats
Linking methods are widely used in the social sciences to compare group differences regarding the mean and the standard deviation of a factor variable. This article examines a comparison between robust Haberman linking (HL) and invariance alignment (IA ...
Alexander Robitzsch
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy