Results 131 to 140 of about 1,174,621 (314)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Palladium Oxidative Addition Complexes for Peptide and Protein Cross-linking

open access: yes, 2018
A new method for cysteine–lysine cross-linking in peptides and proteins using palladium oxidative addition complexes is presented. First, a biarylphosphine-supported palladium reagent is used to transfer an aryl group bearing an O-phenyl carbamate ...
Kubota, Koji   +11 more
core   +1 more source

Are Claims Grounded in Data? An Empowering Linking Approach for Misalignment Identification in Online Data-Driven Discussions

open access: yesIEEE Access
Textual content is effectively supported by data visualization in many contexts, allowing readers to assess the written content by looking at data visualizations.
Tiziano Citro   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An Annotative Approach to Better Hyperauthoring and Associative Linking

open access: yes, 2001
Early hypertext visionaries proposed entire online archives of the world's literature, with everything associatively linked to everything else. Today, the most widespread hypertext system is the World-Wide Web (WWW), a publicly accessible and globally ...
Miles-Board, Timothy
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Linking a U.S. Cap-and-Trade System for Greenhouse Gas Emissions: Opportunities, Implications, and Challenges

open access: yes
The long-run cost of a U.S. cap-and-trade system for greenhouse gas (GHG) emissions could be significantly reduced by linking that system with other existing and emerging tradable permit systems for GHG emissions.
Stavins, Robert N., Jaffe, Judson
core  

Homologous Overexpression of Tyrosinase in Trichoderma reesei and Its Application in Glycinin Cross-Linking

open access: yes
Tyrosinase is capable of oxidizing tyrosine residues in proteins, leading to intermolecular protein cross-linking, which could modify the protein network of food and improve the texture of food.
Kaixuan Hou (10941659)   +8 more
core   +1 more source

Low-Temperature Stable α‑Phase Inorganic Perovskite Compounds via Crystal Cross-Linking

open access: yes, 2019
Inorganic perovskite compounds hold promise to improve the stability of perovskite solar cells (PSCs). However, the phase instability and high annealing temperature process of these metastable structural polymorphs such as α-phase CsPbI3–xBrx hinder ...
Xikui Wang (6170126)   +15 more
core   +1 more source

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