Results 141 to 150 of about 1,174,621 (314)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
eBank UK linking research data, scholarly communication and learning
, 2004 This paper presents an overview of the changing landscape of scholarly communication and describes outcomes from the innovative eBank UK project, which seeks to build links from e-research through to e-learning.
Gutteridge, Christopher J. +13 more
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, 2019 Dynamic bonding is a key factor for self-healing and stimuli-response polymeric materials. However, a detailed molecular-level understanding on effects from dynamic bond break and reform from interchain and intrachain cross-linking remains unclear. Here,
Xiangyang Zhu +11 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Rethinking Library Linking Breathing New Life into OpenURL
This issue of Library Technology Reports provides practicing librarians with real-world examples and strategies for improving resolver usability and functionality in their own institutions.Cover -- Title -- Copyright -- Contents -- Chapter 1-Introduction
Price, Jason., Trainor, Cindi.
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Looking for Linking: Associative Links on the Web
, 2002 Non-trivial hypertexts (containing more than one node) use links to implement their internal structure. On the Web navigation bars have become ubiquitous, defining functional regions on a web page that expose a site’s primary structure, listing nearby ...
Miles-Board, Timothy +2 more
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Click Cross-Linking-Improved Waterborne Polymers for Environment-Friendly Coatings and Adhesives
, 2016 Waterborne polymers, including waterborne polyurethanes (WPU), polyester dispersions (PED), and polyacrylate emulsions (PAE), are employed as environmentally friendly water-based coatings and adhesives.
Qiyao Li (2565205) +11 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source