Results 51 to 60 of about 2,878,980 (272)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Linking results of key and supplementary comparisons of AC/DC voltage transfer references
A regional key comparison (KC) COOMET.EM-K6.a and a supplementary comparison (SC) COOMET.EM-S1 of AC/DC voltage transfer references were conducted between participating laboratories from the Eurasian region.
Velychko Oleh
doaj +1 more source
Medial/skeletal linking structures for multi-region configurations [PDF]
We consider a generic configuration of regions, consisting of a collection of distinct compact regions $\{\Omega_i\}$ in $\mathbb{R}^{n+1}$ which may be either smooth regions disjoint from the others or regions which meet on their piecewise smooth ...
Damon, James, Gasparovic, Ellen
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Higher-dimensional linking integrals
We derive an integral formula for the linking number of two submanifolds of the n-sphere S^n, of the product S^n x R^m, and of other manifolds which appear as "nice" hypersurfaces in Euclidean space. The formulas are geometrically meaningful in that they
Shonkwiler, Clayton +1 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
In this paper, we introduce the tied links, i.e. ordinary links provided with some “ties” between strands. The motivation for introducing such objects originates from a diagrammatical interpretation of the defining generators of the so-called algebra of braids and ties; indeed, one half of such generators can be interpreted as the usual generators of ...
Aicardi, Francesca, Juyumaya, Jesús
openaire +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Linking Error Estimation in Haberman Linking
Haberman linking is a widely used method for comparing groups using the two-parameter logistic item response model. However, the traditional Haberman linking approach relies on joint item parameter estimation, which prevents the application of standard M-
Alexander Robitzsch
doaj +1 more source

