Results 131 to 140 of about 170,550 (343)

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Synthesis of conjugated linoleic acid in ruminants and humans

, 2014
Biomedical studies have provided evidence that one or more isomers of conjugated linoleic acid (CLA) may have beneficial effects in the prevention of human chronic disease. Ruminant meat and milk are the principle source of CLA in the human diet.
Wallace, R. J., K. J. Shingfield, Shingfield, Kevin, R. J. Wallace   +3 more
core   +1 more source

A Green Amphoteric Surfactant Derived From Rapeseed Oil for Enhanced Oil Recovery From Carbonate Acidic Oil Reservoirs

Journal of Surfactants and Detergents, EarlyView.
The Green Amphoteric Surfactant Derived From Rapeseed Oil for Enhanced Oil Recovery From Carbonate Acidic Oil Reservoirs. ABSTRACT Surfactants with both positive and negative functional groups (amphoteric or zwitterionic) are particularly advantageous in acidic oil reservoirs because they remain stable under harsh chemical conditions, tolerate acidic ...
Iman Nowrouzi, Amir H. Mohammadi, Abbas Khaksar Manshad   +2 more
wiley   +1 more source

Safflower (<i>Carthamus tinctorius</i> L.) Seed Oils: Effect of Extraction Process and Cultivars on Chemical Composition, Physicochemical Parameters and Nutritional Quality Index. [PDF]

Food Sci Nutr
M. pulegium essential oil study emphasizes molecular structure analysis and bioactivity. Chemical composition varies based on geographical origin. In silico analyses confirm binding affinities. Essential oil shows potent insecticidal activity with LD50 and LT50.
El Kourchi C, Belhoussaine O, Ali RM, Amakhmakh M, Sumaily KM, Santanatoglia A, Maggi F, Caprioli G, Bouyahya A, Tabyaouı M, Harhar H.   +10 more
europepmc   +2 more sources

Conjugated Linoleic Acid and dairy cows: metabolism, reproduction and products quality

, 2010
The aim of this dissertation was to evaluate in dairy cows the effects of the supplementation of Conjugated Linoleic Acid, as natural feed (pasture) or as additive (CLA rumen protected), on quality of dairy products and on cow metabolism and ...
Esposito, Giulia
core  

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Factors affecting fatty acid composition in forage and milk [PDF]

, 2009
The aims of the studies underlying this thesis were to evaluate variations in fatty acid (FA) contents of plants used as forage for dairy cows in northern Sweden, and their effects on the FA contents of the milk.
Arvidsson, Katarina
core  

Characterization of functional metabolites in broccoli by‐product using green extraction with supercritical fluids

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to valorize broccoli by‐products (leaves and stems) through the extraction of bioactive compounds using supercritical fluid extraction (SFE). The influence of broccoli variety, plant part and maturation stage on total phenolic content (TPC), antioxidant activity and antimicrobial properties was evaluated ...
Iris Gudiño, Rocío Casquete, María José Benito, María de Guía Córdoba, María Henar Prieto, Alberto Martín   +5 more
wiley   +1 more source