Results 151 to 160 of about 895,121 (257)

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

Cancer Science, EarlyView.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon, Min Young Lee, Jiwon Koh, Ki Yong Hong, Junji Fukuda, Sung Joon Kim, Yang‐Sook Chun   +6 more
wiley   +1 more source

Bidirectional Associations Between Circulating Polyunsaturated Fatty Acids and Female Reproductive Endocrine-Related Diseases: A Mendelian Randomization Study. [PDF]

Int J Womens Health
Pan Y, Jiang J, Sun F.
europepmc   +1 more source

Dietary Soybean vs. Palm Oils Differ in Effects on Liver Fat in Adults With MAFLD: A 16‐Week, Double‐Masked, Randomized Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Dietary linoleic acid (LA)‐rich oils reduce liver fat in healthy adults who are not otherwise undergoing weight loss strategies. Effects on the liver fat in adults with fatty liver disease are unknown. Objective The objective of this randomized double‐masked controlled trial was to compare the effects of a dietary soybean oil (SO ...
Martha A. Belury, Rachel M. Cole, Ai Ni, Arunark Kolipaka, Manjunathan Nanjappa, Kristin Thompson, Ali Kalhori, Stephan Zarich, Rolando E. Choriego, Rafael Jimenez‐Flores, Na Li   +10 more
wiley   +1 more source

Activation of human brown adipocytes alters the plasma fatty acid profile. [PDF]

Front Mol Biosci
Miniewska K, Mojsak P, Chmielewska S, Choinska P, Godzien J, Labieniec L, Andrejczuk A, Hannukainen J, Oikonen V, Virtanen K, Nuutila P, Ciborowski M, Maliszewska K, Kretowski AJ.   +13 more
europepmc   +1 more source

The effect of caste, mass and colony identity on rescue priorities in the red imported fire ant

Ecological Entomology, EarlyView.
Fire ants will rescue brood when the brood becomes trapped underground. We find that rescuers may use odor cues to locate trapped rescue targets. We demonstrate that a single reproductive larva is preferentially rescued over a single worker larva, but that caches of multiple worker larvae receive equal treatment as a single reproductive larva.
Paige B. Caine, Natalie Nejad, Daniel I. Goldman, Michael A. D. Goodisman   +3 more
wiley   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

The stability of fatty acid composition in sunflower oil is dependent on environment and affected by structural variation. [PDF]

Theor Appl Genet
Ingold M, Gao Q, Mandel JR, McNellie JP, Keepers KG, Barb JG, Burke JM, Rieseberg LH, Hulke BS.   +8 more
europepmc   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Salt eustress modulates physiological responses and enhances yield, nutritional quality, and antioxidant capacity in sunflower microgreens. [PDF]

BMC Plant Biol
Mickky B, Shams Eldeen R, Elnajar M.
europepmc   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source