Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira +6 more
wiley +1 more source
Effects of Levothyroxine and Liothyronine on Cirrhotic Cardiomyopathy in Rats
In liver cirrhosis, there is low T3 syndrome associated with a decrease in total triiodothyronine (T3) and free T3 concentrations and cirrhotic cardiomyopathy (CCM) with chronotropic incompetence. Thus, we aimed to investigate the effects of eliminating
Razieh Mohammad Jafari +7 more
doaj +1 more source
A Binding Mode Hypothesis of Tiagabine Confirms Liothyronine Effect on γ-Aminobutyric Acid Transporter 1 (GAT1) [PDF]
Andreas Jurik +5 more
openalex +1 more source
Thyroid Signaling Biomarkers in Female Symptomatic Hypothyroid Patients on Liothyronine versus Levothyroxine Monotherapy: A Randomized Crossover Trial [PDF]
Betty Ann Bjerkreim +5 more
openalex +1 more source
Case Report and Literature Review: Intrathyroid Thymic Carcinoma
This case report highlights the challenges in diagnosing intrathyroid thymic carcinoma (ITTC), a rare thyroid tumor, and underscores the importance of postoperative pathology for confirmation. The study emphasizes the good prognosis of ITTC with appropriate surgical management.
Jia‐Yue Sun +3 more
wiley +1 more source
Validation of grizzly bear hair hormone profiles as a tool to monitor population demographics
We measured 16 steroid and thyroid hormone concentrations in grizzly bear hair to predict sex, age class, and reproductive status. Models were highly accurate when predicting sex and age class and showed promise for assessing reproductive status. Results illustrate the potential for hair hormone profiles as non‐invasive population monitoring tools ...
Abbey E. Wilson +10 more
wiley +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura +18 more
wiley +1 more source
Thyroid hormone use in clinical practice by Israeli endocrinologists: a THESIS* questionnaire survey
Objective Several thyroid hormone formulations are available for treatment of hypothyroidism. This study aimed at evaluating the use of these treatment options by Israeli endocrinologists in various clinical scenarios.
Liat Sasson +9 more
doaj +1 more source

