Results 111 to 120 of about 2,262 (235)

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source

Thyroid hormone use in clinical practice by Israeli endocrinologists: a THESIS* questionnaire survey

Thyroid Research
Objective Several thyroid hormone formulations are available for treatment of hypothyroidism. This study aimed at evaluating the use of these treatment options by Israeli endocrinologists in various clinical scenarios.
Liat Sasson, Keren Kaminer, Chagit Adler Cohen, Laszlo Hegedüs, Roberto Negro, Endre V. Nagy, Enrico Papini, Petros Perros, Roberto Attanasio, Eyal Robenshtok   +9 more
doaj   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, Volume 13, Issue 50, 7 September 2026.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Serum Levels of Thyroid Hormones in Relation to Breast Cancer Prognosis: A Multicentre Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
High free T3 levels at diagnosis are associated with good survival following breast cancer. ABSTRACT Thyroid function has been suggested to be associated with breast cancer risk, but not much is known about thyroid hormones as a potential prognostic factor for breast cancer. This study investigated the relation between thyroid hormones in breast cancer
Annie Brange, Ylva Heyman, Kamil Demircan, Johan Vallon‐Christersson, Martin Malmberg, Lao H. Saal, Lisa Rydén, Åke Borg, Lutz Schomburg, Jonas Manjer   +9 more
wiley   +1 more source

New Treatments And Lt3 (Liothyronine) Combinations / Alternative Therapies

This article reviews new approaches to the treatment of hypothyroidism, specifically the combination of levothyroxine (LT4) and liothyronine (LT3), as well as alternative therapies.
Djalalidinova Odina Odilovna, Karimova Muqima Muhammadsodikovna   +1 more
core   +1 more source

Unlocking the Hepatoprotective Potential of Urolithin A in High‐Fat Diet‐Induced MASLD: Integrated Role of Oxidative Stress, Inflammation, FXR/PPAR‐α, and Fibrotic Pathway

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT “Metabolic dysfunction–associated steatotic liver disease” (MASLD) is marked by hepatic steatosis, oxidative stress, inflammation, and fibrosis. Urolithin A (Uro A), a metabolite of ellagitannins, exhibits anti‐inflammatory, antioxidant, and metabolic regulatory activities.
Hamad Alsaykhan, Amany Mohamed Shalaby, Walaa Arafa Keshk, Shahd Saad El‐dien Kamel, Sulaiman Mohammed Alnasser, Mohammed Alorini, Fatima A. Jaber, Mohamed Ali Alabiad, Amr Mohamed Younes, Hanim Magdy Abdelnour   +9 more
wiley   +1 more source

A Binding Mode Hypothesis of Tiagabine Confirms Liothyronine Effect on γ‑Aminobutyric Acid Transporter 1 (GAT1)

, 2015
: Elevating GABA levels in the synaptic cleft by inhibiting its reuptake carrier GAT1 is an established approach for the treatment of CNS disorders like epilepsy.
Andreas Jurik, Thomas Stockner, Gerhard F. Ecker, Harald H. Sitte (1354368), Gerhard F. Ecker (221470), Harald H. Sitte, Barbara Zdrazil (676840), Marion Holy, Barbara Zdrazil, Marion Holy (1354371), Andreas Jurik (1354365), Thomas Stockner (247892)   +11 more
core   +1 more source

From gene regulation to membrane excitability: A new role for thyroid hormone in skeletal muscle

The Journal of Physiology, EarlyView.
Eric N. Jimenez‐Vazquez, David K. Jones   +1 more
wiley   +1 more source

Delayed Recognition of Anti‐NMDAR Encephalitis Mimicking Primary Psychiatric Illness: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) encephalitis frequently presents with prominent psychiatric symptoms, often mimicking primary psychiatric disorders and posing a significant diagnostic challenge. We report the case of a 33‐year‐old woman who presented with a 10‐day history of acute behavioral and psychiatric symptoms initially ...
Bhumika Ghimire, Jagat Bhatt, Saugat Niraula, Bibek Shrestha, Arun Batsa Lamsal, Shreeram Upadhyaya   +5 more
wiley   +1 more source