Results 101 to 110 of about 2,262 (235)

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

Hypothyroidism resulting from follicular‐compact thyroid carcinoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 13‐year‐old, spayed, female beagle, weighing 21 kg, was presented with a cervical nodule that had appeared about 15 days earlier. On palpation, a firm, slightly mobile mass measuring approximately 4 cm in diameter was detected in the thyroid region.
Júlio César Nascimento de Cerqueira Júnior, Teresa Alessandra de Lima Núñez, Ana Beatriz de Souza da Silva, Alessandre Hataka, Priscylla Tatiana Chalfun Guimarães Okamato   +4 more
wiley   +1 more source

EFFICACY OF COMBINED LEVOTHYROXINE AND LIOTHYRONINE AS COMPARED WITH LEVOTHYROXINE MONOTHERAPY IN PRIMARY HYPOTHYROIDISM: A RANDOMIZED CONTROLLED TRIAL

, 2009
Objectives. To examine the efficacy of combination therapy with levothyroxine and liothyronine in improvement of general health, psychological problems, and metabolic status in primary hypothyroidism. Methods.
Valizadeh, M, Musavinasab, N, Hajibeigloo, H, Hayatbakhsh, MR, Momtazi, S, Seyyed-Majidi, MR   +5 more
core   +1 more source

Malignancy in Pediatric Hyperfunctioning Thyroid Nodules: A Case Report and Literature Review

Clinical Endocrinology, Volume 105, Issue 4, Page 474-485, October 2026.
ABSTRACT Background Thyroid nodules are rare in children but carry a markedly higher risk of malignancy compared to adults (20%–26% vs. 5%). Hyperfunctioning thyroid nodules are exceptionally uncommon in the pediatric population and are typically benign.
Cristina Clausi, Simona Censi, Jacopo Maria Arnone, Giulia Messina, Ilaria Piva, Fausto Cortese, Loris Bertazza, Susi Barollo, Francesca Galuppini, Marco Zarantonello, Maurizio Iacobone, Gianmaria Pennelli, Caterina Mian   +12 more
wiley   +1 more source

Effect of levothyroxine plus liothyronine combination therapy on hypothyroid patients quality of life [PDF]

, 2020
BackgroundLiothyronine combination with Levothyroxine(T4-T3) has been tried to improve the quality of life among hypothyroid patients on levothyroxine immunotherapy and normal thyroxine stimulating hormone levels.
Eyad Muwaffaq Alsaqqa; Internal Medicine Resident, King Salman Armed Forced Hospital, Tabuk, Saudi Arabia, Mohammed Ali Alshehri; Medical Intern, Faculty of Medicine, University of Tabuk, Saudi Arabia, Ibrahim Mahmoud Ajwah; Internal Medicine Resident, King Salman Armed Forced Hospital, Tabuk, Saudi Arabia, Hyder Osman Mirghani; Department of Internal Medicine, Faculty of Medicine, University of Tabuk, Saudi Arabia, Ebtesam Saleem Alatawi; Medical Intern, Faculty of Medicine, University of Tabuk, Saudi Arabia, Abdullah Mahmoud Ajwah; Internal Medicine Resident, King Salman Armed Forced Hospital, Tabuk, Saudi Arabia, Omniyyah Ahmed Alnahyah; Medical Intern, Faculty of Medicine, University of Tabuk, Saudi Arabia, Hanaa Masaad Albalawi; Internal Medicine Resident, King Salman Armed Forced Hospital, Tabuk, Saudi Arabia   +7 more
core  

What Is Your Diagnosis? Superficial Cervical Lymph Node Cytology

Veterinary Clinical Pathology, EarlyView.
Vinicius N. Hirata, Rúbia S. da Silva, Francisca B. Lang, Augusto de Oliveira, Cinthia M. de Andrade   +4 more
wiley   +1 more source

METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
METTL18 is essential for histidine Nτ‐methylation of proteins, normal embryonic development, iron and lipid metabolism, and hormone signaling pathways that support postnatal growth in mice. The main points of this study are as follows: First, mouse METTL18 catalyzes histidine Nτ‐methylation. Next, Mettl18 KO embryos are significantly smaller than their
Fumiya Kasai, Jun‐Dal Kim, Koichiro Kako, Naoto Muromachi, Takeru Saito, Yao Yuan, Hayase Mizukami, Nana Kishikawa, Kanako Nakamura, Kaori Motomura, Hiroaki Daitoku, Yuuki Imai, Sho Sekiguchi, Kazuhiko Horiguchi, Satoshi Narumi, Masanobu Yamada, Akiyoshi Fukamizu   +16 more
wiley   +1 more source

Effects of Levothyroxine and Liothyronine on Cirrhotic Cardiomyopathy in Rats

Acta Medica Iranica
In liver cirrhosis, there is low T3 syndrome associated with a decrease in total triiodothyronine (T3) and free T3 concentrations and cirrhotic cardiomyopathy (CCM) with chronotropic incompetence. Thus, we aimed to investigate the effects of eliminating
Razieh Mohammad Jafari, Dlshad Mohammed, Seyed Mohammad Tavangar, Golnar Eftekhari, Maryam Shokrian Zeini, Arash Khodadoostan, Ahmad Reza Dehpour, Farahnaz Jazaeri   +7 more
doaj   +1 more source

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Eight trained males completed 4 days of normal‐carbohydrate or low‐carbohydrate (81% reduction in carbohydrate) diets while maintaining energy balance and undertaking daily exercise. Low carbohydrate decreased total body water and fat‐free mass, increased circulating free fatty acids, glycerol and β‐hydroxybutyrate, alongside increased fat oxidation at
Erick Mosquera‐Lopez, Harry L. Taylor, Yusuke Nishimura, Carl Langan‐Evans, Sam O. Shepherd, Juliette A. Strauss, James P. Morton, Jatin G. Burniston, Jose L. Areta   +8 more
wiley   +1 more source

HIGH RESOLUTION FREE TRIIODOTHYRONINE-THYROTROPIN (FT3-TSH) RESPONSES TO A SINGLE ORAL DOSE OF LIOTHYRONINE IN HUMANS: EVIDENCE OF DISTINCT INTER-INDIVIDUAL DIFFERENCES UNRAVELED USING AN ELECTRICAL NETWORK MODEL

, 2017
The effects of a single oral dose of liothyronine (L-T3) on thyroid stimulating hormone (TSH) and other related thyroid system parameters are partly understood despite therapeutic use of this hormone over many decades.
JACQUELINE JONKLAAS, MELVIN KHEE-SHING LEOW, KEITH R. LATHAM, SIMON L. GOEDE   +3 more
core   +1 more source