Results 131 to 140 of about 2,262 (235)

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen   +6 more
wiley   +1 more source

Exploration of a Multimodal Machine Learning Model Integrating Ultrasound and Clinical Indicators for the Diagnosis of Diabetic Peripheral Neuropathy

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 9, Page 1863-1876, September 2026.
Objectives Based on ultrasound technology and clinical indicators, this study intends to develop multiple risk prediction models for diabetic peripheral neuropathy (DPN), conduct comparative analyses of these models, and further evaluate and validate the diagnostic efficacy of the optimal model for DPN as well as its potential in clinical application ...
Bo‐yu She   +4 more
wiley   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

Determination of B1 2, iodine, iodochlorhydroxyquin, liothyronine, thyroxine and zinc sulfate in drugs by neutron activation analysis

open access: yes, 1984
Instrumental neutron activation analysis was used in this study for the determination of the elements cobalt, iodine, and zinc in pharmaceutical dosage forms in order to develop a simple, fast and accurate method for their quantitation in these products.
Kanias, G.D., Choulis, N.H.
core   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li   +3 more
wiley   +1 more source

Unraveling the Metabolic‐Cardiovascular Disease Nexus: An Epidemiological Network Analysis Identifies Central Indicators

open access: yesMedComm, Volume 7, Issue 9, September 2026.
In the STONE cohort with 4752 Shanghai citizens, the CardioMet12 CVD scoring system was established by clustering individuals across seven metabolic dimensions. Based on analysis from Chinese and US epidemiological cohorts and network analysis, CardioMet12 emerges as a robust metric that considers the complex interplay among metabolic disorders ...
Xin‐yi Cai   +10 more
wiley   +1 more source

The Relationship Between Dysglycemia and Dyslipidemia in First‐Episode, Untreated Chinese Patients With Major Depressive Disorder at Different Ages of Onset

open access: yesEarly Intervention in Psychiatry, Volume 20, Issue 9, September 2026.
ABSTRACT Purpose Dysglycemia, a common ailment in MDD patients, lacks research regarding its variance across the age of onset (AOO). Therefore, we investigated the correlation between fasting blood glucose (FBG) abnormalities and blood lipids in first‐onset, untreated patients with MDD and to determine the factors that influence glycemic abnormalities ...
Hang Tan   +4 more
wiley   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

open access: yesOrthopaedic Surgery, Volume 18, Issue 9, Page 1785-1803, September 2026.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu   +4 more
wiley   +1 more source

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