Results 71 to 80 of about 116,137 (336)

Hydrolysis of Edible Oils by Fungal Lipases: An Effective Tool to Produce Bioactive Extracts with Antioxidant and Antimicrobial Potential [PDF]

, 2022
Alexandra Kotogán, Zsófia Terézia Furka, Tamás Kovács‐Öller, Bettina Volford, Dóra Anna Papp, Mónika Varga, Thu Huỳnh, András Szekeres, Tamás Papp, Csaba Vágvölgyi, Keshab Chandra Mondal, Erika Beáta Kerekes, Miklós Takó   +12 more
openalex   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Characterization of the extracellular lipase of Bacillus subtilis and its relationship to a membrane-bound lipase found in a mutant strain [PDF]

, 1979
Bacillus subtilis CMK33 is a mutant that is more osmotically fragile than the wild type when it is converted to the protoplast form. The protoplasts of this mutant contain a membrane-bound lipase, which is not found in protoplasts of the wild type ...
Kennedy, Mary B., Lennarz, W. J.
core  

Untargeted Lipidomic Analysis to Broadly Characterize the Effects of Pathogenic and Non-Pathogenic Staphylococci on Mammalian Lipids [PDF]

, 2018
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the ...
Baker, Paul RS, Contaifer, Daniel, Jr., Ekroos, Kim, Jefferson, Kimberly K., Kumar, Naren Gajenthra, Wijesinghe, Dayanjan S.   +5 more
core   +4 more sources

Controllable Water-Triggered Degradation of PCL Solution-Blown Nanofibrous Webs Made Possible by Lipase Enzyme Entrapment [PDF]

, 2023
Md. Asaduzzaman, Sonja Salmon
openalex   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Lipases: biocatalizadores da hidrólise de triacilglicerois [PDF]

, 2012
Os enzimas lipases (E.C.3.1.1.3) pertencem à família das serinas hidrolases, que por sua vez incluem várias enzimas esterases (E.C.3.1.1.1). Uma característica que distingue as lipases das esterases é o facto de serem capazes de realizar a hidrólise de ...
Choupina, Altino, Vaz, Madalena
core  

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]

, 2010
Peer reviewedPublisher ...
Barabas, Klaudia, Cameron, Gary, Harkany, Tibor, Keimpema, Erik, Mackie, Ken, Morozov, Yury M, Torii, Masaaki, Tortoriello, Giuseppe, Watanabe, Masahiko, Yanagawa, Yuchio   +9 more
core   +1 more source

Analysis of Bacterial Isolates Capable of Partially Degrading Polyethylene Terephthalate [PDF]

Brazilian Archives of Biology and Technology
In this work, we studied 46 bacterial isolates to determine their potential for polyethylene terephthalate (PET) degradation. Only eight lipase-positive isolates were pre-selected to continue analysis.
Ana Sofía Fierros-Peña, Maribel Mireles-Martínez, Jorge Alberto Torres-Ortega, Marco Antonio Garza-Navarro, Jesús Manuel Villegas-Mendoza, Ninfa María Rosas-García   +5 more
doaj   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source