Results 41 to 50 of about 1,407,276 (168)

Comparative gene identification 58/α/β hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity

Journal of Lipid Research, 2014
Mutations in the gene encoding comparative gene identification 58 (CGI-58)/α/β hydrolase domain 5 (ABHD5) cause Chanarin-Dorfman syndrome, characterized by excessive triacylglycerol storage in cells and tissues.
Derek McMahon, Anna Dinh, Daniel Kurz, Dharika Shah, Gil-Soo Han, George M. Carman, Dawn L. Brasaemle   +6 more
doaj   +1 more source

Activated platelets secrete a protein-like factor that stimulates oxidized-LDL receptor activity in macrophages.

Journal of Lipid Research, 1991
Platelet secretory products were shown to modulate the interaction between lipoproteins and their receptors on macrophages. Preincubation of macrophages for 2 h at 37 degrees C with platelet conditioned medium (PCM), followed by its removal and a further
B Fuhrman, GJ Brook, M Aviram
doaj   +1 more source

Sex-dependent relationship of polymorphisms in CLOCK and REV-ERBα genes with body mass index and lipid levels in children

Scientific Reports, 2023
Circadian rhythms, which are governed by a circadian clock, regulate important biological processes associated with obesity. SNPs in circadian clock genes have been linked to energy and lipid homeostasis.
Claudia Vales-Villamarín, Olaya de Dios, Ignacio Mahíllo-Fernández, Macarena Perales, Iris Pérez-Nadador, Teresa Gavela-Pérez, Leandro Soriano-Guillén, Carmen Garcés   +7 more
doaj   +1 more source

Phosphatidylcholine biosynthesis is required for secretion of truncated apolipoprotein Bs from McArdle RH7777 cells only when a neutral lipid core is formed

Journal of Lipid Research, 1997
Decreased phosphatidylcholine biosynthesis inhibits the secretion of very low density lipoproteins from hepatocytes (Yao, Z. and D. E. Vance. 1988. J. Biol. Chem. 263: 2998-3004).
P S Vermeulen, S Lingrell, Z Yao, D E Vance   +3 more
doaj   +1 more source

Thumba (Citrullus colocynthis L.) seed oil: a potential bio-lubricant base-stock

Grasas y Aceites, 2015
Thumba seed oil, a minor, renewable tree borne oil, was exploited for the preparation of biolubricant base-stocks. The different base-stocks prepared were epoxy thumba oil (ETO), branched, 2-ethylhexyl ester (T2-EtHE), and polyol esters, namely ...
K. Kamalakar, G. N.V.T. Sai Manoj, R. B.N. Prasad, M. S.L. Karuna   +3 more
doaj   +1 more source

Utilization of different fatty acids for hepatic and biliary phosphatidylcholine formation and the effect of changes in phosphatidylcholine molecular species on biliary lipid secretion.

Journal of Lipid Research, 1991
Biliary cholesterol secretion is ordinarily tightly coupled to phosphatidylcholine (PC) secretion. Bile PCs are distinct in composition and predominantly composed of molecular species with 16:0 in the sn-1 position and 18:2 and 18:1 in the sn-2 position.
SJ Robins, JM Fasulo, VF Robins, GM Patton   +3 more
doaj   +1 more source

Shared genetic loci for body fat storage and adipocyte lipolysis in humans

Scientific Reports, 2022
Total body fat and central fat distribution are heritable traits and well-established predictors of adverse metabolic outcomes. Lipolysis is the process responsible for the hydrolysis of triacylglycerols stored in adipocytes.
Agné Kulyté, Veroniqa Lundbäck, Peter Arner, Rona J. Strawbridge, Ingrid Dahlman   +4 more
doaj   +1 more source

Postprandial lipemia differentially influences high density lipoprotein subpopulations LpAI and LpAI,AII.

Journal of Lipid Research, 1994
The behavior of apolipoprotein-defined subpopulations LpAI and LpAI,AII within high density lipoprotein (HDL) subclasses 2 and 3 was analyzed in the postprandial phase after a fat load.
R W James, D Pometta
doaj   +1 more source

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

Journal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira, K Nilausen, H Meinertz, EC Quintão   +3 more
doaj   +1 more source

Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency1

Journal of Lipid Research, 2008
Our aim was to characterize HDL subspecies and fat-soluble vitamin levels in a kindred with familial apolipoprotein A-I (apoA-I) deficiency. Sequencing of the APOA1 gene revealed a nonsense mutation at codon −2, Q[−2]X, with two documented homozygotes ...
Raul D. Santos, Ernst J. Schaefer, Bela F. Asztalos, Eliana Polisecki, Jian Wang, Robert A. Hegele, Lilton R.C. Martinez, Marcio H. Miname, Carlos E. Rochitte, Protasio L. Da Luz, Raul C. Maranhão   +10 more
doaj   +1 more source