Results 71 to 80 of about 1,789,531 (316)

Single embryo and oocyte lipid fingerprinting by mass spectrometry

, 2010
Methods used for lipid analysis in embryos and oocytes usually involve selective lipid extraction from a pool of many samples followed by chemical manipulation, separation and characterization of individual components by chromatographic techniques ...
Santos, Luiz Fernando A, Garcia, Jerusa S, GARCIA, Jerusa S., CATHARINO, Rodrigo R., BERTOLLA, Ricardo P., Bertolla, Ricardo P, BASSO, Andrea C., GOZZO, Fabio C., PERECIN, Felipe, Lo Turco, Edson G, Sanvido, Gustavo B, Lo Turco, Edson G. [UNIFESP], Basso, Andréa C, Meirelles, Flávio V, MEIRELLES, Flvio V., SARAIVA, Sergio A., SARTORI, Roberto, PONTES, Jose Henrique F., Ferreira, Christina R, Sangalli, Juliano R, Bertolla, Ricardo P. [UNIFESP], Pontes, José Henrique F, Eberlin, Marcos N, SANGALLI, Juliano R., Guardieiro, Monique M, EBERLIN, Marcos N., GUARDIEIRO, Monique M., TURCO, Edson G. Lo, FERREIRA, Christina R., SANVIDO, Gustavo B., SANTOS, Luiz Fernando A., Catharino, Rodrigo R, Saraiva, Sergio A, Gozzo, Fabio C   +33 more
core   +1 more source

Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice

, 2020
Treatments with supplemental oxygen in premature infants can impair lung development, leading to bronchopulmonary dysplasia (BPD). Although a stage-specific alteration of lung lipidome occurs during postnatal lung development, whether neonatal hyperoxia,
Hongwei Yao, Abigail L. Peterson, Jennifer F. Carr, Xiangming Ji, Phyllis A. Dennery   +4 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus.

, 2003
Diabetes mellitus (DM) is associated with enhanced lipid oxidation and persistent platelet activation. We investigated whether oxidant stress (OS) also affects circulating proteins and is associated with an abnormal coagulative pattern.
De Cristofaro, Raimondo, Landolfi, Raffaele, Patrono, Carlo, Rocca, Bianca   +3 more
core  

Aggregation of Lipid A Variants: a Hybrid Particle-Field Model

, 2019
Lipid A is one of three components of bacterial lipopolysaccharides (constituting the outer membrane of Gram-negative bacteria) and is recognized to have an important biological role in inflammatory response of the immune system.
Sigbjørn Løland, Bore, Thereza A., Soares, Antonio, De Nicola, G. J. Agur, Sevink, Giuseppe, Milano, Michele, Cascella   +5 more
core   +1 more source

Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System [PDF]

, 2009
In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths
Zimnicka, Magdalena, Joanna Kaminska, Burzynska, Beata, Kania Magdalena, Wysocka-Kapcinska, Monika, Beata Burzynska, Witold Danikiewicz, Danikiewicz Witold, Plochocka, Danuta, Leszczynska, Agata, Leszczynska Agata, Zimnicka Magdalena, Danikiewicz, Witold, Wysocka-Kapcinska Monika, Magdalena Kania, Kiliszek Marek, Marek Kiliszek, Kaminska Joanna, Agata Leszczynska, Danuta Plochocka, Magdalena Zimnicka, Kaminska, Joanna, Plochocka Danuta, Szkopinska, Anna, Anna Szkopinska, Kania, Magdalena, Kiliszek, Marek, Szkopinska Anna, Monika Wysocka-Kapcinska, Burzynska Beata   +29 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Lipid Content in the Sea Urchin Embryos under Nickel Stress

, 2009
Nickel is a heavy metal toxic for living organisms even at low concentrations. Sea urchin embryos represent a good model system for testing the effects of physical and chemical stress, like heavy metals, on development and cell viability.
황진익, 이택견, 박소윤, 류태권   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Temperature-Dependence of Lipid A Acyl Structure in Psychrobacter cryohalolentis and Arctic Isolates of Colwellia hornerae and Colwellia piezophila

Marine Drugs, 2015
Lipid A is a fundamental Gram-negative outer membrane component and the essential element of lipopolysaccharide (endotoxin), a potent immunostimulatory molecule.
Charles R. Sweet, Rebecca E. Watson, Corinne A. Landis, Joseph P. Smith   +3 more
doaj   +1 more source