Results 201 to 210 of about 484,984 (311)

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

Effect of Mulberry Leaf and Its Active Component, 1-Deoxynojirimycin, on Palmitic Acid-Induced Lipid Accumulation in HepG2 Cells. [PDF]

Biomedicines
Lee D, Kim J, Han MJ, Kim SH, Kim TH, Eom DW, Song I, Jeong D, Yamabe N, Kim KH.   +9 more
europepmc   +1 more source

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

Advanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid, Aishik Chakraborty, Wei Luo, Juhi Bora, John Joseph Kelly, John Andrew Ronald, Arghya Paul   +6 more
wiley   +1 more source

Engineering central metabolism in Yarrowia lipolytica increases lipid accumulation

Tadej Markuš, Mladen Soldat, Vasilka Magdevska, Jaka Horvat, Martin Kavšček, Gregor Kosec, Štefan Fujs, Uroš Petrovič   +7 more
openalex   +1 more source

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

Advanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy, Chuan‐En Lu, Kai Liu, Audrey Gallud   +3 more
wiley   +1 more source

Association of lipid accumulation product with mortality in patients with diabetes mellitus. [PDF]

Sci Rep
Pan D, Chen P, Ji S, Zhang H, Chen T.
europepmc   +1 more source

Insufficient Lymph Drainage Causes Abnormal Lipid Accumulation and Vein Wall Degeneration

, 2016
Hiroki Tanaka, Naoto Yamamoto, Minoru Suzuki, Yuuki Mano, Masaki Sano, Nobuhiro Zaima, Takeshi Sasaki, Mitsutoshi Setou, Naoki Unno   +8 more
openalex   +2 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

NEDD4L knockdown reduced lipid accumulation in non-alcoholic fatty liver disease by promoting the activity of PI3K/AKT signaling pathway. [PDF]

Eur J Med Res
Zhou J, Li W, Chi X, Li D, Yang C, Duan Z.   +5 more
europepmc   +1 more source

Carbon Contacts to Proteins Enable Robust, Biocompatible Electronic Junctions with Near‐Activation‐less Conduction Down to 10 K

Advanced Functional Materials, EarlyView.
A robust solid‐state protein junction with a semi‐transparent eC/Au electrode allows photoexcitation of the bacterio‐rhodopsin, bR layer, to isomerize the bR retinal. The resulting photo‐response shows the protein is functional in the solid‐state junction.
Shailendra K. Saxena, Sudipta Bera, Tatyana Bendikov, Israel Pecht, Mordechai Sheves, David Cahen   +5 more
wiley   +1 more source