Results 201 to 210 of about 3,287,800 (353)

Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]

, 2015
Dolan, Sharron, Graham, Annette, Soffientini, Ugo   +2 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes. [PDF]

Am J Physiol Endocrinol Metab
Shimada BK, Ogawa-Wong AN, Soares AG, Hallam KA, Santiago PJD, Saelua K, Nakahara-Akita KK, Torres DJ, Brockman JD, Kurokawa S, Ewell KL, Bellinger MT, Toh P, Lagatta Pamplona Remedios G, Alfulaij N, Swanson SM, Seyedali A, Zavacki AM, Berry MJ, Seale LA.   +19 more
europepmc   +1 more source

Hypercholesterolemia and lipid accumulation in chondrocytes [PDF]

Osteoarthritis and Cartilage, 2013
Kuroki, K., Bozynski, C., Stoker, A., Laughlin, M.H., Cook, J.L.   +4 more
openaire   +1 more source

Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co‐Existence of Whitlockite Crystals and Carbonated Hydroxyapatite‐Mineralized Collagen Fibrils

Advanced Functional Materials, EarlyView.
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden, Carolien T. A Kuster, Amber van Broekhoven, Raphaela Allgayer, Luco Rutten, Rona Roverts, Marta Cerruti, Elena Macías‐Sánchez, Jan Hein Cornel, Salloua el Messaoudi, Anat Akiva, Nico Sommerdijk   +11 more
wiley   +1 more source

Targeting GPR68 Alleviates Inflammation and Lipid Accumulation in Metabolic Dysfunction-Associated Steatohepatitis. [PDF]

Biology (Basel)
Wei J, Wang L, Mao Z, Zhang P.
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Fatty acid-induced lipid accumulation promotes radiosensitization in Huh7 hepatocellular carcinoma cells. [PDF]

Oncol Lett
Tanaka H, Mariya Y, Monzen S.
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Functional and Structural Insights into Lipases Associated with Fruit Lipid Accumulation in Swida wilsoniana. [PDF]

Biomolecules
Wu W, Chen Y, Li C, Li P, Yang Y, Jiang L, Yuan W, Liu Q, Li L, Zeng W, Zhou X, Chen J.   +11 more
europepmc   +1 more source