Results 91 to 100 of about 4,174,905 (243)

Association between lipid accumulation products and mortality outcomes in patients with osteoporosis and osteopenia

Experimental Gerontology
Background: Osteoporosis (OP) and osteopenia are metabolic bone disorders associated with increased fragility and fracture risk. While lipid accumulation products (LAP) are emerging as potential markers of metabolic health, their prognostic significance ...
Yazhou Liu, Ying Yang, Yuhao Li, Wenbo Ding, Xiaodong Yang   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome.

, 2009
We evaluated the role of sterol-regulatory element binding protein (SREBP)-1c/peroxisome proliferator activated receptor- * (PPAR * ) pathway on heart lipotoxicity in patients with metabolic syndrome (MS) and aortic stenosis (AS).
SINISCALCHI N., CACCIAPUOTI, Federico, DI FILIPPO, Clara, BARBIERI, Michelangela, ROSSI, Francesco, PAOLISSO, Giuseppe, D'AMICO, Michele, PORTOGHESE M., FERRARACCIO, Franca, MARFELLA, Raffaele   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Role of transcription factors in storage lipid accumulation in plants

, 2012
With few exceptions, seeds oil accumulates as triacylglycerols; three fatty acid molecules esterified to a glycerol backbone. The synthesis of normal fatty acids and unusual fatty acids, their assembly into triacylglycerols and subsequent packaging to ...
Fobert, Pierre R.
core   +1 more source

Influence of body fat on heart rate variability in healthy females

Journal of the Pakistan Medical Association
Objective: To evaluate the effect of central obesity indices in healthy females on cardiac autonomic activity, using heart rate variability as an index reflecting the cardiac autonomic balance.
Hiba Salih Mahdi Al-Khassaki, Bassam Talib Al-Galani   +1 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Ο ρόλος του δείκτη συσσώρευσης λιπιδίων (Lipid Accumulation Product) ως μεταβολικός δείκτης στο σύνδρομο πολυκυστικών ωοθηκών

, 2023
Το σύνδρομο πολυκυστικών ωοθηκών (ΣΠΩ) αποτελεί μια από τις πιο διαδεδομένες ενδοκρινικές διαταραχές που επηρεάζουν γυναίκες αναπαραγωγικής ηλικίας, και χαρακτηρίζεται κυρίως από υπερανδρογονισμό, ανωορρηξία και πολυκυστικές ωοθήκες.
Προκοπάκης Ιωάννης, Prokopakis Ioannis   +1 more
core   +1 more source