Results 151 to 160 of about 219,006 (336)

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

open access: yesAdvanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee   +5 more
wiley   +1 more source

Modulation of elasticity and interactions in charged lipid multibilayers: monovalent salt solutions

open access: yes, 2016
We have studied the electrostatic screening effect of NaCl solutions on the interactions between anionic lipid bilayers in the fluid lamellar phase using a Poisson-Boltzmann based mean-field approach with constant charge and constant potential limiting ...
Belička, Michal   +4 more
core   +3 more sources

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

Energy landscape for the insertion of amphiphilic nanoparticles into lipid membranes: A computational study.

open access: yesPLoS ONE, 2019
Amphiphilic, monolayer-protected gold nanoparticles (NPs) have been shown to enter cells via a non-endocytic, non-disruptive pathway that could be valuable for biomedical applications.
Reid C Van Lehn, Alfredo Alexander-Katz
doaj   +1 more source

Coupling of Solute and Solvent Flows in Porous Lipid Bilayer Membranes [PDF]

open access: bronze, 1971
Thomas E. Andreoli   +2 more
openalex   +1 more source

Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing

open access: yesAdvanced Materials, EarlyView.
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko   +2 more
wiley   +1 more source

Fluorescence of Supported Phospholipid Bilayers Recorded in a Conventional Horizontal-Beam Spectrofluorometer [PDF]

open access: yes, 2016
Supported phospholipid bilayers are a convenient model of cellular membranes in studies of membrane biophysics and protein-lipid interactions. Traditionally, supported lipid bilayers are formed on a flat surface of a glass slide to be observed through ...
Kovrigin, Evgeni L.   +1 more
core   +1 more source

The OpenPicoAmp : an open-source planar lipid bilayer amplifier for hands-on learning of neuroscience

open access: yes, 2014
Neuroscience education can be promoted by the availability of low cost and engaging teaching materials. To address this issue, we developed an open-source lipid bilayer amplifier, the OpenPicoAmp, which is appropriate for use in introductory courses in ...
Dupuis, Freddy   +2 more
core   +3 more sources

Home - About - Disclaimer - Privacy