Results 161 to 170 of about 112,656 (211)
Correction to Gaffney et al., Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +1 more source
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European Biophysics Journal, 1985
The softening of wet lipid bilayer membranes during their gel-to-fluid first-order phase transition is studied by computer simulation of a family of two-dimensional microscopic interaction models. The models include a variable number, q, of lipid chain conformational states, where 2 less than or equal to q less than or equal to 10.
O G, Mouritsen, M J, Zuckermann
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The softening of wet lipid bilayer membranes during their gel-to-fluid first-order phase transition is studied by computer simulation of a family of two-dimensional microscopic interaction models. The models include a variable number, q, of lipid chain conformational states, where 2 less than or equal to q less than or equal to 10.
O G, Mouritsen, M J, Zuckermann
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Nanoparticle–lipid bilayer interactions studied with lipid bilayer arrays
Nanoscale, 2015Cationic and anionic polystyrene nanoparticles were screened for lipid bilayer interactions with different solutions, bilayer compositions, and particle charges.
Bin, Lu, Tyler, Smith, Jacob J, Schmidt
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Texture of Lipid Bilayer Domains
Journal of the American Chemical Society, 2009We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are well studied, the possibility of texture in gel domains ...
Jensen, Uffe Bernchou; id_orcid 0000-0002-5309-2696 +5 more
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2015
Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D, Nickels, John, Katsaras
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Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D, Nickels, John, Katsaras
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Multiscale modeling of lipids and lipid bilayers
European Biophysics Journal, 2005A multiscale modeling approach is applied for simulations of lipids and lipid assemblies on mesoscale. First, molecular dynamics simulation of initially disordered system of lipid molecules in water within all-atomic model was carried out. On the next stage, structural data obtained from the molecular dynamics (MD) simulation were used to build a ...
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Paclitaxel Partitioning into Lipid Bilayers
Journal of Pharmaceutical Sciences, 1996Paclitaxel (taxol) is diterpenoid anticancer drug with a new mechanism of cytostatic action. It is under investigation in clinical trials for treatment of various types of human cancer. A major difficulty in developing paclitaxel as a chemotherapeutic agent in its poor water solubility.
Wenk, M. R. +3 more
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Structure of Oriented Lipid Bilayers
Nature New Biology, 1971X-ray diffraction studies show that lipid hydrocarbon chains are uniformly packed in bilayers and oriented so that their free ends are near the centre. This provides a model for biological membranes.
Y K, Levine, M H, Wilkins
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Binding of glucagon to lipid bilayers
Biochemistry and Cell Biology, 1990At physiological pH and temperature, glucagon binds to liposomes composed of egg phosphatidylcholine and cholesterol (2:1 mol/mol) in a highly specific manner. The chemical reactivities of the functional groups were determined over the concentration range of 1.0 × 10−6 – 3.0 × 10−8 M by the method of competitive labelling with 1-fluoro-2,4 ...
R P, Oomen, H, Kaplan
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Interaction of antihistamines with lipid bilayers
Biochemical Pharmacology, 1979Abstract Interaction between a variety of antihistamines and lipid bilayers has been studied. The H 1 -antagonists all reduce the phase transition temperature of dipalmitoyl phosphatidylcholine, and these data have been used to calculate binding constants for the drug to lipid. The H 2 -antagonists cimetidine and metiamide have no effect on the lipid
E K, Rooney, M G, Gore, A G, Lee
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