Results 171 to 180 of about 199,281 (229)

Coronal Complexation Induces Snowman‐Shaped Janus Polymersome Formation

Angewandte Chemie, EarlyView.
Snowman‐like Janus polymersomes were produced in a simple, yet versatile two‐step approach involving a plasticizing agent and a cationic polymer additive to complex with the charged polymersome. Shape transformation was driven by coronal complexation altering membrane structure, followed by segregation of the polymer additive to form a protruding bleb ...
Rebecca Y. Lai, Chin Ken Wong, Martina H. Stenzel   +2 more
wiley   +2 more sources

Fluorescence imaging of lamellipodin-mediated biomolecular condensates on solid supported lipid bilayer membranes. [PDF]

Methods Enzymol
Narayan KB, Baeyens L, James HP, Swain A, Baumgart T.   +4 more
europepmc   +1 more source

MemPrep, a new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress. [PDF]

EMBO J
Reinhard J, Starke L, Klose C, Haberkant P, Hammarén H, Stein F, Klein O, Berhorst C, Stumpf H, Sáenz JP, Hub J, Schuldiner M, Ernst R.   +12 more
europepmc   +1 more source

Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A Channel. [PDF]

Int J Mol Sci
Rostovtseva TK, Weinrich M, Jacobs D, Rosencrans WM, Bezrukov SM.   +4 more
europepmc   +1 more source

Binding and dimerization of PGLa peptides in anionic lipid bilayer studied by replica exchange molecular dynamics. [PDF]

Sci Rep
Bowers SR, Lockhart C, Klimov DK.
europepmc   +1 more source

A Single‐Molecule Liposome Assay for Membrane Permeabilization

Angewandte Chemie International Edition, EarlyView.
The rapid screening of compounds capable of disrupting or permeabilizing biological membranes is essential to the search for new therapeutics. Here, we present an ultrasensitive single‐molecule confocal microscopy assay combined with fast‐flow microfluidics to study membrane permeabilization in large unilamellar vesicles (LUVs).
Krzysztof M. Bąk, Daniel C. Edwards, Dylan George, Bhanu Singh, Ryan Ferguson, Tianxiao Zhao, Kristin Piché, Ariel Louwrier, Scott L. Cockroft, Mathew H. Horrocks   +9 more
wiley   +1 more source

Design and Construction of a Multi-Tiered Minimal Actin Cortex for Structural Support in Lipid Bilayer Applications. [PDF]

ACS Appl Bio Mater
Smith AJ, Larsen TRB, Zimmerman HK, Virolainen SJ, Meyer JJ, Keranen Burden LM, Burden DL.   +6 more
europepmc   +1 more source

On the Thermodynamics of Water Displacement from Binding Sites and its Contributions to Supramolecular and Biomolecular Affinity

Angewandte Chemie International Edition, Accepted Article.
The role of water displacement in noncovalent binding has been debated in the fields of supramolecular chemistry and drug design. We use molecular dynamics simulations of idealized host‐guest systems to address the long‐standing controversy of whether water is merely a bystander or an actual driver of noncovalent binding in aqueous solution. To isolate
Jeffry Setiadi, Frank Biedermann, Werner M. Nau, Michael K. Gilson   +3 more
wiley   +1 more source

ARV1 deficiency induces lipid bilayer stress and enhances rDNA stability by activating the unfolded protein response in Saccharomyces cerevisiae. [PDF]

J Biol Chem
Hong S, Lee HG, Huh WK.
europepmc   +1 more source

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

Angewandte Chemie International Edition, Accepted Article.
Protein‐based tools are emerging as innovative solutions to interfere with biological pathways in molecular biology and medicine. They offer advantages over traditional small molecules due to their adaptable structural diversity and their ability to engage previously inaccessible cellular targets.
Jonathan Franke, Jan Vincent V. Arafiles, Leis Christian, Christian Hackenberger   +3 more
wiley   +1 more source