Results 201 to 210 of about 199,281 (229)
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European Biophysics Journal, 1985
The softening of wet lipid bilayer membranes during their gel-to-fluid first-order phase transition is studied by computer simulation of a family of two-dimensional microscopic interaction models. The models include a variable number, q, of lipid chain conformational states, where 2 less than or equal to q less than or equal to 10.
Ole G. Mouritsen, Martin J. Zuckermann
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The softening of wet lipid bilayer membranes during their gel-to-fluid first-order phase transition is studied by computer simulation of a family of two-dimensional microscopic interaction models. The models include a variable number, q, of lipid chain conformational states, where 2 less than or equal to q less than or equal to 10.
Ole G. Mouritsen, Martin J. Zuckermann
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Nanoparticle–lipid bilayer interactions studied with lipid bilayer arrays
Nanoscale, 2015Cationic and anionic polystyrene nanoparticles were screened for lipid bilayer interactions with different solutions, bilayer compositions, and particle charges.
Tyler Smith, Bin Lu, Jacob J. Schmidt
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2015
Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D. Nickels, John Katsaras
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Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D. Nickels, John Katsaras
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Texture of Lipid Bilayer Domains
Journal of the American Chemical Society, 2009We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are well studied, the possibility of texture in gel domains ...
Jensen, Uffe Bernchou+5 more
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Paclitaxel Partitioning into Lipid Bilayers
Journal of Pharmaceutical Sciences, 1996Paclitaxel (taxol) is diterpenoid anticancer drug with a new mechanism of cytostatic action. It is under investigation in clinical trials for treatment of various types of human cancer. A major difficulty in developing paclitaxel as a chemotherapeutic agent in its poor water solubility.
Wenk, M. R.+3 more
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Liposomes and lipid bilayers in biosensors
Advances in Colloid and Interface Science, 2017Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in healthcare, drug discovery, food safety, and environmental monitoring. Although a number of sensing concepts and devices have been developed, many longstanding challenges to obtain inexpensive, easy-to-use, and reliable sensor platforms remain largely unmet ...
Mazur, Federico+3 more
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Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array
2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012This paper describes a method for the formation of a lipid bilayer on a droplet-based chamber array. This method enables us to form small chambers sealed with lipid bilayers easily. The lipid membranes are stable and remain for at least 1 day. We successfully observed a transmembrane phenomenon via the lipid membrane on a droplet by fluorescent ...
Taishi Tonooka, Shoji Takeuchi
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NMR Spectroscopy of Lipid Bilayers
2010Knowledge of lipid structure and dynamics in a membranous environment is of first importance for deciphering cellular function. Sterols and sphingolipids are key molecules in maintaining membrane integrity and are the building blocks of membrane domains, such as "rafts".
Grélard, A.+3 more
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Multiscale modeling of lipids and lipid bilayers
European Biophysics Journal, 2005A multiscale modeling approach is applied for simulations of lipids and lipid assemblies on mesoscale. First, molecular dynamics simulation of initially disordered system of lipid molecules in water within all-atomic model was carried out. On the next stage, structural data obtained from the molecular dynamics (MD) simulation were used to build a ...
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Monolayers and bilayers of lipids
Colloids and Surfaces, 1991Abstract The spreading monolayers of ceramides alone and in mixtures with monooleoyl glycerol were studied at the air/water interface in the 15-30°C temperature range. The bidimensional phases were determined from the spreading isotherms of the pure components, whereas the interfacial miscibility of the compounds being studied was deduced from the ...
Gabriella Gabrielli+3 more
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