Results 201 to 210 of about 199,281 (229)
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Softening of lipid bilayers

European Biophysics Journal, 1985
The softening of wet lipid bilayer membranes during their gel-to-fluid first-order phase transition is studied by computer simulation of a family of two-dimensional microscopic interaction models. The models include a variable number, q, of lipid chain conformational states, where 2 less than or equal to q less than or equal to 10.
Ole G. Mouritsen, Martin J. Zuckermann
openaire   +3 more sources

Nanoparticle–lipid bilayer interactions studied with lipid bilayer arrays

Nanoscale, 2015
Cationic and anionic polystyrene nanoparticles were screened for lipid bilayer interactions with different solutions, bilayer compositions, and particle charges.
Tyler Smith, Bin Lu, Jacob J. Schmidt
openaire   +3 more sources

Water and Lipid Bilayers

2015
Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D. Nickels, John Katsaras
openaire   +3 more sources

Texture of Lipid Bilayer Domains

Journal of the American Chemical Society, 2009
We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are well studied, the possibility of texture in gel domains ...
Jensen, Uffe Bernchou   +5 more
openaire   +4 more sources

Paclitaxel Partitioning into Lipid Bilayers

Journal of Pharmaceutical Sciences, 1996
Paclitaxel (taxol) is diterpenoid anticancer drug with a new mechanism of cytostatic action. It is under investigation in clinical trials for treatment of various types of human cancer. A major difficulty in developing paclitaxel as a chemotherapeutic agent in its poor water solubility.
Wenk, M. R.   +3 more
openaire   +3 more sources

Liposomes and lipid bilayers in biosensors

Advances in Colloid and Interface Science, 2017
Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in healthcare, drug discovery, food safety, and environmental monitoring. Although a number of sensing concepts and devices have been developed, many longstanding challenges to obtain inexpensive, easy-to-use, and reliable sensor platforms remain largely unmet ...
Mazur, Federico   +3 more
openaire   +4 more sources

Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array

2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012
This paper describes a method for the formation of a lipid bilayer on a droplet-based chamber array. This method enables us to form small chambers sealed with lipid bilayers easily. The lipid membranes are stable and remain for at least 1 day. We successfully observed a transmembrane phenomenon via the lipid membrane on a droplet by fluorescent ...
Taishi Tonooka, Shoji Takeuchi
openaire   +2 more sources

NMR Spectroscopy of Lipid Bilayers

2010
Knowledge of lipid structure and dynamics in a membranous environment is of first importance for deciphering cellular function. Sterols and sphingolipids are key molecules in maintaining membrane integrity and are the building blocks of membrane domains, such as "rafts".
Grélard, A.   +3 more
openaire   +4 more sources

Multiscale modeling of lipids and lipid bilayers

European Biophysics Journal, 2005
A multiscale modeling approach is applied for simulations of lipids and lipid assemblies on mesoscale. First, molecular dynamics simulation of initially disordered system of lipid molecules in water within all-atomic model was carried out. On the next stage, structural data obtained from the molecular dynamics (MD) simulation were used to build a ...
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Monolayers and bilayers of lipids

Colloids and Surfaces, 1991
Abstract The spreading monolayers of ceramides alone and in mixtures with monooleoyl glycerol were studied at the air/water interface in the 15-30°C temperature range. The bidimensional phases were determined from the spreading isotherms of the pure components, whereas the interfacial miscibility of the compounds being studied was deduced from the ...
Gabriella Gabrielli   +3 more
openaire   +2 more sources

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