Results 261 to 270 of about 140,194 (304)
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Structure of Oriented Lipid Bilayers
Nature New Biology, 1971X-ray diffraction studies show that lipid hydrocarbon chains are uniformly packed in bilayers and oriented so that their free ends are near the centre. This provides a model for biological membranes.
Y K, Levine, M H, Wilkins
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Binding of glucagon to lipid bilayers
Biochemistry and Cell Biology, 1990At physiological pH and temperature, glucagon binds to liposomes composed of egg phosphatidylcholine and cholesterol (2:1 mol/mol) in a highly specific manner. The chemical reactivities of the functional groups were determined over the concentration range of 1.0 × 10−6 – 3.0 × 10−8 M by the method of competitive labelling with 1-fluoro-2,4 ...
R P, Oomen, H, Kaplan
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Interaction of antihistamines with lipid bilayers
Biochemical Pharmacology, 1979Abstract Interaction between a variety of antihistamines and lipid bilayers has been studied. The H 1 -antagonists all reduce the phase transition temperature of dipalmitoyl phosphatidylcholine, and these data have been used to calculate binding constants for the drug to lipid. The H 2 -antagonists cimetidine and metiamide have no effect on the lipid
E K, Rooney, M G, Gore, A G, Lee
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Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array
2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012This paper describes a method for the formation of a lipid bilayer on a droplet-based chamber array. This method enables us to form small chambers sealed with lipid bilayers easily. The lipid membranes are stable and remain for at least 1 day. We successfully observed a transmembrane phenomenon via the lipid membrane on a droplet by fluorescent ...
T. Tonooka, S. Takeuchi
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Liposomes and lipid bilayers in biosensors
Advances in Colloid and Interface Science, 2017Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in healthcare, drug discovery, food safety, and environmental monitoring. Although a number of sensing concepts and devices have been developed, many longstanding challenges to obtain inexpensive, easy-to-use, and reliable sensor platforms remain largely unmet ...
Federico, Mazur +3 more
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Photoelectrospectrometry of bilayer lipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1980These different bilayer lipid membrane systems were studied under visible and ultraviolet illumination. The first system consisted of a bilayer lipid membrane formed with a mixture of phospholipids and cholesterol, to one side of which purple membrane fragments from Halobacterium halobium were added.
J R, Lopez, H T, Tien
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The formation of lipid bilayers on surfaces
Colloids and Surfaces B: Biointerfaces, 2009The adsorption of biological molecules at solid-liquid interfaces is growing in importance due to its application to a very broad range of fields. Biomimetic systems like phospholipid mono- or bilayers are used to study such adsorption processes in great detail.
Gromelski, S. +3 more
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Adsorption of proteins on a lipid bilayer
European Biophysics Journal, 2010In our analysis of protein adsorption on a lipid bilayer, the protein surface is considered to contain one or a few charged spots, and the bilayer contains a significant amount of lipids with oppositely charged head groups. After adsorption, a folded protein is assumed to change its shape slightly due to the electrostatic attraction, so that one of the
Vladimir P, Zhdanov, Bengt, Kasemo
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Immobilization of proteins to lipid bilayers
Biosensors and Bioelectronics, 1996Phospholipid bilayers deposited on sensor surfaces are excellent substrates for immobilizing proteins via a molecular anchor. An integrated optics sensing device was used to accurately measure the binding kinetics of proteins thus anchored. By comparing the results with measurements using proteins from which the anchor had been enzymatically removed ...
Ramsden JJ, Bachmanova GI, Archakov AI
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NMR Spectroscopy of Lipid Bilayers
2010Knowledge of lipid structure and dynamics in a membranous environment is of first importance for deciphering cellular function. Sterols and sphingolipids are key molecules in maintaining membrane integrity and are the building blocks of membrane domains, such as "rafts".
Axelle, Grélard +3 more
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