Results 271 to 280 of about 229,223 (348)

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

MemPrep, a new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress. [PDF]

EMBO J
Reinhard J, Starke L, Klose C, Haberkant P, Hammarén H, Stein F, Klein O, Berhorst C, Stumpf H, Sáenz JP, Hub J, Schuldiner M, Ernst R.   +12 more
europepmc   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A Channel. [PDF]

Int J Mol Sci
Rostovtseva TK, Weinrich M, Jacobs D, Rosencrans WM, Bezrukov SM.   +4 more
europepmc   +1 more source

Chiral Recognition of Lipid Bilayer Membranes by Supramolecular Assemblies of Peptide Amphiphiles

, 2019
Kohei Sato, Wei Ji, Zaida Álvarez, Liam C. Palmer, Samuel I. Stupp   +4 more
openalex   +2 more sources

Thermometric Based‐Microswimmers with Chemical and Optical Engines

Advanced Intelligent Systems, EarlyView.
Temperature sensing at small scales is typically performed using passive luminescent particles. Here, an alternative approach is demonstrated by integrating upconversion thermometry into self‐propelled microswimmers powered by chemical fuels or light. This strategy offers a step toward dynamic thermal sensing at the microscale, relevant to both lab‐on ...
João M. Gonçalves, Katherine Villa
wiley   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

Binding and dimerization of PGLa peptides in anionic lipid bilayer studied by replica exchange molecular dynamics. [PDF]

Sci Rep
Bowers SR, Lockhart C, Klimov DK.
europepmc   +1 more source

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

Advanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang, Jie Chen, Yunmiao Ma, Qingwei Zhou, Yu Kong, Yingxiang Chen, Junjie Chi, Haihua Hu   +7 more
wiley   +1 more source