Structure and activity of lipid bilayer within a membrane-protein transporter
Significance Membrane proteins function naturally as imbedded in the lipid bilayers of cell membranes, but isolation into homogeneous and soluble preparations is needed for many biochemical studies. Detergents, which are used traditionally to extract and
W. Qiu+7 more
semanticscholar +1 more source
Molecular Dynamics Simulation of the Interaction Between Benzanthrone Dye and Model Lipid Membranes
The benzanthrone fluorescent dyes are known as environmentally-sensitive reporters for exploring the physicochemical properties and structural alterations of lipid membranes.
Olga Zhytniakivska
doaj +1 more source
Electrostatics of lipid bilayer bending
The electrostatic contribution to spontaneous membrane curvature is calculated within Poisson-Boltzmann theory under a variety of assumptions and emphasizing parameters in the physiological range. Asymmetric surface charges, either fixed with respect to bilayer midplane area, or with respect to the lipid-water area both induce curvature but of opposite
Marko V. Jarić+2 more
openaire +4 more sources
Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β*
The aggregation of amyloid-β (Aβ) on lipid bilayers has been implicated as a mechanism by which Aβ exerts its toxicity in Alzheimer's disease (AD). Lipid bilayer thinning has been observed during both oxidative stress and protein aggregation in AD, but ...
K. Korshavn+10 more
semanticscholar +1 more source
The Power of Asymmetry: Architecture and Assembly of the Gram-Negative Outer Membrane Lipid Bilayer.
Determining the chemical composition of biological materials is paramount to the study of natural phenomena. Here, we describe the composition of model gram-negative outer membranes, focusing on the predominant assembly, an asymmetrical bilayer of lipid ...
M. Chevrette+9 more
semanticscholar +1 more source
Supported Lipid Bilayers of Escherichia coli Extracted Lipids and Their Calcium Dependence
Formation of supported lipid bilayer (SLB) and additional structures of Escherichia coli (E. coli) lipids were investigated with fluorescence microscopy and atomic force microscopy.
Yasuhiro Kakimoto, Ryugo Tero
doaj +1 more source
Lipid/water interface of galactolipid bilayers in different lyotropic liquid-crystalline phases
In this study, carried out using computational methods, the organisation of the lipid/water interface of bilayers composed of galactolipids with both α-linolenoyl acyl chains is analysed and compared in three different lyotropic liquid-crystalline phases.
Jakub Hryc+3 more
doaj +1 more source
On Shape Transformations and Shape Fluctuations of Cellular Compartments and Vesicles [PDF]
We discuss the shape formation and shape transitions of simple bilayer vesicles in context with their role in biology. In the first part several classes of shape changes of vesicles of one lipid component are described and it is shown that these can be ...
Berndl K+18 more
core +1 more source
A continuum model of lipid bilayers [PDF]
We study a one-dimensional continuum model for lipid bilayers. The system consists of water and lipid molecules; lipid molecules are represented by two ‘beads’, a head bead and a tail bead, connected by a rigid rod. We derive a simplified model for such a system, in which we only take into account the effects of entropy and hydrophilic/hydrophobic ...
Joke Blom, Mark A. Peletier
openaire +2 more sources
BLM Analyzer: a software tool for experiments on planar lipid bilayers
Planar lipid bilayers represent a versatile platform for studying the functions of various membrane proteins as well as the development of biosensors.
Pavel Novák+2 more
doaj +1 more source