Results 71 to 80 of about 229,223 (348)

Heads and Tails: Molecular Imagination and the Lipid Bilayer, 1917–1941 [PDF]

open access: yes, 2018
Today, the lipid bilayer structure is nearly ubiquitous, taken for granted in even the most rudimentary introductions to cell biology. Yet the image of the lipid bilayer, built out of lipids with heads and tails, went from having obscure origins deep in ...
Liu, Daniel
core  

How Well Can You Tailor the Charge of Lipid Vesicles? [PDF]

open access: yes, 2019
Knowledge and control of surface charge or potential is important for tailoring colloidal interactions. In this work, we compare widely used zeta potential (ζ) measurements of charged lipid vesicle surface potential to direct measurements using the ...
Docto, D   +6 more
core   +2 more sources

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets

open access: yesMembranes, 2017
Amyloid- β aggregates play a causative role in Alzheimer’s disease. These aggregates are a product of the physical environment provided by the basic neuronal membrane, composed of a lipid bilayer.
Adree Khondker   +2 more
doaj   +1 more source

Changes in Electrical Capacitance of Cell Membrane Reflect Drug Partitioning-Induced Alterations in Lipid Bilayer

open access: yesMicromachines, 2023
The plasma membrane is a lipid bilayer that establishes the outer boundary of a living cell. The composition of the lipid bilayer influences the membrane’s biophysical properties, including fluidity, thickness, permeability, phase behavior, charge ...
Shide Bakhtiari   +3 more
doaj   +1 more source

Fast Membranes Hemifusion via Dewetting between Lipid Bilayers

open access: yes, 2014
The behavior of lipid bilayer is important to understand the functionality of cells like the trafficking of ions between cells. Standard procedures to explore the properties of lipid bilayer and hemifused states typically use either supported membranes ...
Fleury, Jean-Baptiste   +2 more
core   +1 more source

Folding and insertion thermodynamics of the transmembrane WALP peptide [PDF]

open access: yes, 2015
The anchor of most integral membrane proteins consists of one or several helices spanning the lipid bilayer. The WALP peptide, GWW(LA)$_n$(L)WWA, is a common model helix to study the fundamentals of protein insertion and folding, as well as helix-helix ...
Chernick M. R.   +6 more
core   +4 more sources

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

open access: yesAdvanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang   +9 more
wiley   +1 more source

A Lipid-Bilayer-On-A-Cup Device for Pumpless Sample Exchange

open access: yesMicromachines, 2020
Lipid-bilayer devices have been studied for on-site sensors in the fields of diagnosis, food and environmental monitoring, and safety/security inspection.
Yoshihisa Ito   +8 more
doaj   +1 more source

Triglyceride blisters in lipid bilayers: implications for lipid droplet biogenesis and the mobile lipid signal in cancer cell membranes. [PDF]

open access: yesPLoS ONE, 2010
Triglycerides have a limited solubility, around 3%, in phosphatidylcholine lipid bilayers. Using millisecond-scale course grained molecular dynamics simulations, we show that the model lipid bilayer can accommodate a higher concentration of triolein (TO)
Himanshu Khandelia   +3 more
doaj   +1 more source

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