Results 311 to 320 of about 125,587 (335)
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Texture of Lipid Bilayer Domains
Journal of the American Chemical Society, 2009We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are well studied, the possibility of texture in gel domains ...
Jensen, Uffe Bernchou +5 more
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Paclitaxel Partitioning into Lipid Bilayers
Journal of Pharmaceutical Sciences, 1996Paclitaxel (taxol) is diterpenoid anticancer drug with a new mechanism of cytostatic action. It is under investigation in clinical trials for treatment of various types of human cancer. A major difficulty in developing paclitaxel as a chemotherapeutic agent in its poor water solubility.
Wenk, M. R. +3 more
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Liposomes and lipid bilayers in biosensors
Advances in Colloid and Interface Science, 2017Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in healthcare, drug discovery, food safety, and environmental monitoring. Although a number of sensing concepts and devices have been developed, many longstanding challenges to obtain inexpensive, easy-to-use, and reliable sensor platforms remain largely unmet ...
Mazur, Federico +3 more
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Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array
2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012This paper describes a method for the formation of a lipid bilayer on a droplet-based chamber array. This method enables us to form small chambers sealed with lipid bilayers easily. The lipid membranes are stable and remain for at least 1 day. We successfully observed a transmembrane phenomenon via the lipid membrane on a droplet by fluorescent ...
Taishi Tonooka, Shoji Takeuchi
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Multiscale modeling of lipids and lipid bilayers
European Biophysics Journal, 2005A multiscale modeling approach is applied for simulations of lipids and lipid assemblies on mesoscale. First, molecular dynamics simulation of initially disordered system of lipid molecules in water within all-atomic model was carried out. On the next stage, structural data obtained from the molecular dynamics (MD) simulation were used to build a ...
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Monolayers and bilayers of lipids
Colloids and Surfaces, 1991Abstract The spreading monolayers of ceramides alone and in mixtures with monooleoyl glycerol were studied at the air/water interface in the 15-30°C temperature range. The bidimensional phases were determined from the spreading isotherms of the pure components, whereas the interfacial miscibility of the compounds being studied was deduced from the ...
Gabriella Gabrielli +3 more
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Binding of glucagon to lipid bilayers
Biochemistry and Cell Biology, 1990At physiological pH and temperature, glucagon binds to liposomes composed of egg phosphatidylcholine and cholesterol (2:1 mol/mol) in a highly specific manner. The chemical reactivities of the functional groups were determined over the concentration range of 1.0 × 10−6 – 3.0 × 10−8 M by the method of competitive labelling with 1-fluoro-2,4 ...
Harvey Kaplan, Raymond P. Oomen
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Interaction of antihistamines with lipid bilayers
Biochemical Pharmacology, 1979Abstract Interaction between a variety of antihistamines and lipid bilayers has been studied. The H 1 -antagonists all reduce the phase transition temperature of dipalmitoyl phosphatidylcholine, and these data have been used to calculate binding constants for the drug to lipid. The H 2 -antagonists cimetidine and metiamide have no effect on the lipid
M.G. Gore, E.K. Rooney, Anthony G. Lee
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Photoelectrospectrometry of bilayer lipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1980These different bilayer lipid membrane systems were studied under visible and ultraviolet illumination. The first system consisted of a bilayer lipid membrane formed with a mixture of phospholipids and cholesterol, to one side of which purple membrane fragments from Halobacterium halobium were added.
Jose R. Lopez, H. Ti Tien
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Electrofusion of Lipid Bilayers
1989Electrostimulated fusion (electrofusion) is one of the promising methods in the study of the somatic hybridization of cells. In spite of a great number of studies in which this phenomenon is used, its mechanism has not been elucidated. Electrofusion, and generally fusion, presupposes the joining of cell membranes and the volumes limited by them ...
Grigory B. Melikyan, L.V. Chernomordik
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