Results 41 to 50 of about 1,686 (274)

Cerebral infarction in diabetes: Clinical pattern, stroke subtypes, and predictors of in-hospital mortality [PDF]

open access: yes, 2005
Background: To compare the characteristics and prognostic features of ischemic stroke in patients with diabetes and without diabetes, and to determine the independent predictors of in-hospital mortality in people with diabetes and ischemic stroke ...
Adrià Arboix   +51 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Aspirin: A review of its neurobiological properties and therapeutic potential for mental illness [PDF]

open access: yes, 2013
There is compelling evidence to support an aetiological role for inflammation, oxidative and nitrosative stress (O&NS), and mitochondrial dysfunction in the pathophysiology of major neuropsychiatric disorders, including depression, schizophrenia, bipolar
Berk, M. (Michael)   +8 more
core   +1 more source

Marine ecosystem connectivity mediated by migrant–resident interactions and the concomitant cross‐system flux of lipids

open access: yesEcology and Evolution, 2016
AbstractAccumulating research argues that migrants influence the functioning and productivity of local habitats and ecosystems along migration routes and potentially drive cross‐system energy fluxes of considerable magnitude, yet empirical documentation of local ecological effects and descriptions of the underlying mechanisms are surprisingly rare.
van Deurs, Mikael   +6 more
openaire   +4 more sources

Biomass Production and Simultaneous Minerals Sequestration from Brewery Wastewater with Concomitant Lipid Accumulation Using Algae

open access: yesChemical Engineering Transactions, 2022
Some industrial wastewaters contain high levels of non-biodegradable organic and inorganic matter, and in-house physical and chemical treatment produces secondary pollutants that are released into the receiving environment and can harm the ecosystem. Over the years, conventional biological treatment of these industrial effluents has proven ineffective.
Kukwa Donald, Chetty Manimagalay
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Comparison of effect of resveratrol and vanadium on diabetes related dyslipidemia and hyperglycemia in streptozotocin induced diabetic rats [PDF]

open access: yes, 2011
Purpose: Resveratrol a natural polyphenolic stilbene derivative has wide variety of biological activities. There is also a large body of evidence demonstrating positive effect of resveratrol in treatment of various metabolic complications including ...
Fatemeh Haidari   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Thermal Sterilization on Physicochemical Stability and Antioxidant Capacity of Flaxseed Milk(热杀菌对亚麻籽乳理化稳定性及抗氧化能力的影响) [PDF]

open access: yesShipin kexue jishu xuebao
Flaxseed, as a functional food raw material, was rich in α-linolenic acid, high-quality proteins, soluble polysaccharides, lignans and other active lipid concomitants, thereby possessing high nutritional value and potential for development and ...
YU Xiao(禹晓)   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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