Results 51 to 60 of about 556 (228)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Zhongguo youzhi探究山桐子果实的基本化学成分与其油脂在成熟过程中的积累变化规律，以确定适宜的山桐子果实采摘时间。对河南南阳、四川凉山、贵州六盘水不同采摘时间的山桐子整果、果肉和种子中的水分、粗脂肪、蛋白质、灰分、总糖、总黄酮、总酚含量及其油脂脂肪酸组成及脂质伴随物（维生素E、β-谷甾醇、角鲨烯）含量进行测定，并对各指标进行相关性分析。结果表明：不同种源山桐子果实的水分、粗脂肪、蛋白质、灰分、总糖、总黄酮、总酚含量及其油脂脂肪酸组成、脂质伴随物含量在不同采摘期以及不同部位之间均存在差异；粗脂肪、灰分、总糖、维生素E ...
宋明发1,2，邹康1，范芳玉1，常云鹤1,2，马立志1,2 SONG Mingfa1,2,ZOU Kang1,FAN Fangyu1,CHANG Yunhe1,2,MA Lizhi1,2
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Shipin yu jixieObjectiveTo explore the extraction efficiency and quality of sea buckthorn seed oil obtained by subcritical butane extraction.MethodsTaking extraction yield as the evaluation index, response surface methodology was adopted to optimize the process ...
NIU Xiaotong +5 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Zhongguo youzhi旨在为牡丹籽油精准适度加工提供参考，将萌发15 d的牡丹籽在120~200 ℃下炒制20 min后榨油，分析炒制温度对牡丹籽出油率及其油脂理化性质、脂质伴随物以及抗氧化能力的影响，并与未萌发牡丹籽进行对比。结果表明：萌发提高了牡丹籽的出油率，且在炒制温度140~160 ℃下具有较高的出油率（22.76%~22.81%）；萌发降低了牡丹籽油的酸值和过氧化值，但使其色泽加深；萌发前后牡丹籽油的脂肪酸组成无变化，不饱和脂肪酸含量随炒制温度的升高而降低；萌发后牡丹籽油的生育酚、植物甾醇、叶绿素、类胡萝卜素、总酚、
汤鸿宇1, ABDIRAKHMAN Dana1, 谢小青1, 黄丹2, 刘重阳3, 刘晓丽1, 李琪1, 于修烛1 TANG Hongyu1, ABDIRAKHMAN Dana1, XIE Xiaoqing1, HUANG Dan2, LIU Chongyang3, LIU Xiaoli1, LI Qi1, YU Xiuzhu1
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