Results 71 to 80 of about 1,686 (274)
Antioxidant vitamin intakes assessed using a food-frequency questionnaire: correlation with biochemical status in smokers and non-smokers [PDF]
, 2017 The increasing interest in the possible role of antioxidant vitamins in many disease states means that methods of assessing vitamin intakes which are suitable for large-scale investigations are now required.
Bolton-Smith, C. +4 more
core
Attenuation of oxidative and nitrosative stress in cortical area associates with antidepressant-like effects of tropisetron in male mice following social isolation stress. [PDF]
, 2016 Tropisetron, a 5-HT3 receptor antagonist widely used as an antiemetic, has been reported to have positive effects on mood disorders. Adolescence is a critical period during the development of brain, where exposure to chronic stress during this time is ...
Amini-Khoei, Hossein. +12 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Zhongguo youzhi探究山桐子果实的基本化学成分与其油脂在成熟过程中的积累变化规律，以确定适宜的山桐子果实采摘时间。对河南南阳、四川凉山、贵州六盘水不同采摘时间的山桐子整果、果肉和种子中的水分、粗脂肪、蛋白质、灰分、总糖、总黄酮、总酚含量及其油脂脂肪酸组成及脂质伴随物（维生素E、β-谷甾醇、角鲨烯）含量进行测定，并对各指标进行相关性分析。结果表明：不同种源山桐子果实的水分、粗脂肪、蛋白质、灰分、总糖、总黄酮、总酚含量及其油脂脂肪酸组成、脂质伴随物含量在不同采摘期以及不同部位之间均存在差异；粗脂肪、灰分、总糖、维生素E ...
宋明发1,2，邹康1，范芳玉1，常云鹤1,2，马立志1,2 SONG Mingfa1,2,ZOU Kang1,FAN Fangyu1,CHANG Yunhe1,2,MA Lizhi1,2
doaj +1 more source
Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes [PDF]
, 2014 We mapped ∼85,000 rare nonsynonymous exonic single nucleotide polymorphisms ( SNPs ) to 17 psychophysiological endophenotypes in 4,905 individuals, including antisaccade eye movements, resting EEG , P 300 amplitude, electrodermal activity, affect ...
Abecasis, Gonçalo +8 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Shipin yu jixieObjectiveTo explore the extraction efficiency and quality of sea buckthorn seed oil obtained by subcritical butane extraction.MethodsTaking extraction yield as the evaluation index, response surface methodology was adopted to optimize the process ...
NIU Xiaotong +5 more
doaj +1 more source
Bioprocessing feasibility analysis [PDF]
The biology and pathophysiology of the thymus gland is discussed and a clinical procedure for thymic hormone assay is described. The separation of null lymphocytes from mice spleens and the functional characteristics of the cells after storage and ...
core +1 more source
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]
, 2015 The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source