Results 211 to 220 of about 3,233,658 (249)

Association Between Lipid-Lowering Therapy and Differences in the Distribution of LDL-C, apoB and non-HDL-C. [PDF]

J Clin Med
Ziółkowski M, Obońska K, Ratajczak J, Adamski P, Banach M, Chlebus K, Grzelakowska K, Jankowski P, Krintus M, Kryś J, Laskowska E, Mrzywka N, Niezgoda P, Ostrowska M, Podhajski P, Skonieczny G, Sosnowska B, Szarpak Ł, Topolska M, Umińska J, Rzepka-Cholasińska A, Navarese EP, Kubica J.   +22 more
europepmc   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

Letter to the Editor regarding: "Lipid-lowering therapy in patients with hypercholesterolemia in terms of the POLSCORE and SCORE2 scales. A single-center retrospective analysis". [PDF]

Cardiol J
Kimura R.
europepmc   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Correction to: Optimizing lipid-lowering therapy for acute coronary syndrome using a decision support system: insights from a cluster randomized trial. [PDF]

Eur Heart J Digit Health
europepmc   +1 more source

Intensive Lipid-Lowering Therapy Following Acute Coronary Syndrome: The Earlier the Better. [PDF]

J Cardiovasc Dev Dis
Pradhan A, Sharma P, Prajapathi S, Aracri M, Iellamo F, Perrone MA.   +5 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Association Between Lipoprotein(a) Testing, Lipid-Lowering Therapy Intensification, and Low-Density Lipoprotein Cholesterol Goal Attainment: Findings From the Veterans Affairs Health System. [PDF]

J Am Heart Assoc
Parsa S, Shah P, Furst A, Dudum R, Din N, Maron D, Heidenreich P, Ward JH, Lozama A, Sandhu AT, Rodriguez F.   +10 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Lipid-lowering therapy in patients with hypercholesterolemia in terms of the POLSCORE and SCORE2 scales. A single-center retrospective analysis. [PDF]

Cardiol J
Rogozik JK, Grabowski M, Główczyńska R.   +2 more
europepmc   +1 more source