Results 51 to 60 of about 3,233,658 (249)

Existing problems and new possibilities in the treatment of dyslipidemia Joint Conclusion Based on the Results of the Expert Council

Рациональная фармакотерапия в кардиологии, 2021
The meeting of the expert council of cardiologists-lipidologists, organized with the support of Novartis and dedicated to the discussion of the existing system of medical care for patients with familial hypercholesterolemia / mixed dyslipidemia, the ...
M. V. Ezhov, V. V. Kukharchuk, I. V. Sergienko, N. M. Akhmedzhanov, M. I. Voevoda, V. S. Gurevich, V. V. Kashtalap, V. O. Konstantinov, V. V. Skibitsky, I. I. Shaposhnik   +9 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

The era of targeted therapy for hyperlipidemia

Российский кардиологический журнал
Despite a variety of lipid-lowering drugs, mostly pelleted, aimed at reducing low-density lipoprotein cholesterol and triglycerides, only a small number of patients achieve their target levels.
U. V. Chubykina, A. V. Tyurina, M. V. Ezhov   +2 more
doaj   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

Reduction in arterial wall strain with aggressive lipid-lowering therapy in patients with carotid artery disease

, 2011
*This article is free to read on the publisher's website*\ud \ud Background: \ud \ud Inflammation and biomechanical factors have been associated with the development of vulnerable atherosclerotic plaques.
Tang, T. Y., Tjun Y Tang, Jonathan H Gillard, Li, Z. Y., Jiang, F., Zhi-Yong Li, Fan Jiang, Gillard, J. H., Zhang, Y., Yun Zhang   +9 more
core   +1 more source

Position paper of the Polish Expert Group on the use of pitavastatin in the treatment of lipid disorders in Poland endorsed by the Polish Lipid Association

Archives of Medical Science, 2023
Lipid disorders, primarily hypercholesterolemia, are the most common cardiovascular (CV) risk factor in Poland (this applies even 3/4 of people). The low-density lipoprotein cholesterol (LDL-C) serum level is the basic lipid parameter that should be ...
Maciej Banach, Stanisław Surma, Agnieszka Kapłon-Cieślicka, Przemysław Mitkowski, Grzegorz Dzida, Tomasz Tomasik, Agnieszka Mastalerz-Migas   +6 more
doaj   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Mind the Gap! - Geographic transferability of economic evaluation in health [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Background: Transferring cost-effectiveness information between geographic domains offers the potential for more efficient use of analytical resources ...
Boehler, Christian Ernst Heinrich
core   +5 more sources

Lipid Lowering Therapy: An Era Beyond Statins. [PDF]

, 2022
Dyslipidemia, specifically elevated LDL cholesterol levels, causes atherosclerotic cardiovascular disease (ASCVD) and increases the risk of myocardial infarction and stroke.
Shah, Rohan, Patel, Neal, Corriero, Anna, Mares, Adriana C, Awuah, Wireko Andrew, Shaikh, Raheel, Capriles, Camilo Andrés Avendaño, Abdul-Rahman, Toufik, Bukhari, Syed Muhammad Awais, Herrera, Emiliano Cantu, de Andrade, Heloisa, Ahmad, Shahzaib, Gupta, Rahul, MD, Goel, Akshay, Lawrence, Jannel, Ulusan, Sebahat, Hajra, Adrija, Bandyopadhyay, Dhrubajyoti   +17 more
core   +1 more source