Results 41 to 50 of about 847,311 (317)

Aglycon diversity of brain sterylglucosides: structure determination of cholesteryl- and sitosterylglucoside[S]

Journal of Lipid Research, 2016
To date, sterylglucosides have been reported to be present in various fungi, plants, and animals. In bacteria, such as Helicobacter pylori, proton NMR spectral analysis of isolated 1-O-cholesteryl-β-d-glucopyranoside (GlcChol) demonstrated the presence ...
Hisako Akiyama, Kazuki Nakajima, Yoshiyuki Itoh, Tomoko Sayano, Yoko Ohashi, Yoshiki Yamaguchi, Peter Greimel, Yoshio Hirabayashi   +7 more
doaj   +1 more source

Visualizing NBD-lipid Uptake in Mammalian Cells by Confocal Microscopy

Bio-Protocol, 2023
Eukaryotic cells use a series of membrane transporters to control the movement of lipids across their plasma membrane. Several tools and techniques have been developed to analyze the activity of these transporters in the plasma membrane of mammalian ...
Julia Baum, Lasse Bredegaard, Sara Herrera, Thomas Günther Pomorski   +3 more
doaj   +1 more source

Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion

, 2006
The study of ion channels and other membrane proteins and their potential use as biosensors and drug screening targets require their reconstitution in an artificial membrane.
Fisher, K.H., Berry, RM, Fisher, K H, Berry, R M, de Planque, MR, de Planque, M R R, Sandison, ME, Watts, A, Mendes, G P, Morgan, Hywel, Watts, A., Berry, Richard, Sandison, M E, de Planque, M.R.R., Sandison, Mairi E., Mendes, GP, Zagnoni, M, Zagnoni, Michele, Watts, Anthony, Berry, R.M., Morgan, H, Mendes, G.P., Fisher, KH   +22 more
core   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
core   +1 more source

Modeling and Simulation of Lipid Membranes

Membranes, 2022
Cell membranes separate the interior of cells and the exterior environment, providing protection, controlling the passage of substances, and governing the interaction with other biomolecules and signalling processes [...]
Jordi Martí, Carles Calero
openaire   +7 more sources

The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis

, 2007
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Periasamy Selvaraj, Timothy P. Tolentino, Cheng Zhu   +2 more
core   +1 more source

Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]

, 1979
Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Schirrmacher, V., B Morein, V Schirrmacher, Koszinowski, Ulrich H., Morein, B., D Barz, Barz, D., U Koszinowski   +7 more
core   +1 more source

Functional Peptides from SARS-CoV-2 Binding with Cell Membrane: From Molecular Dynamics Simulations to Cell Demonstration

Cells, 2022
Herein, we have verified the interaction between the functional peptides from the SARS-CoV-2 and cell membrane, and we further proved that peptides exhibit little membrane disruption.
Yun Hao, Rongrong Wu, Fenghua Wang, Liwei Zhang, Zengkai Wang, Xiaolu Song, Lei Liu   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source