Results 21 to 30 of about 2,400,496 (300)

Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity[S]

Journal of Lipid Research, 2015
Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of SM and with cholesterol in type C.
Susi Anheuser, Bernadette Breiden, Günter Schwarzmann, Konrad Sandhoff   +3 more
doaj   +1 more source

Partial synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification

Journal of Lipid Research, 2014
Within recent years, ganglioside patterns have been increasingly analyzed by MS. However, internal standards for calibration are only available for gangliosides GM1, GM2, and GM3.
Martin Gantner, Günter Schwarzmann, Konrad Sandhoff, Thomas Kolter   +3 more
doaj   +1 more source

Plasmon Waveguide Resonance: Principles, Applications and Historical Perspectives on Instrument Development

Molecules, 2021
Plasmon waveguide resonance (PWR) is a variant of surface plasmon resonance (SPR) that was invented about two decades ago at the University of Arizona.
Estelle Rascol, Sandrine Villette, Etienne Harté, Isabel D. Alves   +3 more
doaj   +1 more source

Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase

Journal of Lipid Research, 2017
Glucosylceramide (GlcCer) is the primary storage lipid in the lysosomes of Gaucher patients and a secondary one in Niemann-Pick disease types A, B, and C.
Misbaudeen Abdul-Hammed, Bernadette Breiden, Günter Schwarzmann, Konrad Sandhoff   +3 more
doaj   +1 more source

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2[S]

Journal of Lipid Research, 2014
During endocytosis, membrane components move to intraluminal vesicles of the endolysosomal compartment for digestion. At the late endosomes, cholesterol is sorted out mainly by two sterol-binding proteins, Niemann-Pick protein type C (NPC)1 and NPC2.
Vincent O. Oninla, Bernadette Breiden, Jonathan O. Babalola, Konrad Sandhoff   +3 more
doaj   +1 more source

Hydrophobic Mismatch Controls the Mode of Membrane-Mediated Interactions of Transmembrane Peptides

Membranes, 2022
Various cellular processes require the concerted cooperative action of proteins. The possibility for such synchronization implies the occurrence of specific long-range interactions between the involved protein participants.
Oleg V. Kondrashov, Peter I. Kuzmin, Sergey A. Akimov   +2 more
doaj   +1 more source

Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion

, 2006
The study of ion channels and other membrane proteins and their potential use as biosensors and drug screening targets require their reconstitution in an artificial membrane.
Zagnoni, M, Fisher, K H, Berry, R M, de Planque, M R R, Watts, A, Mendes, G P, Morgan, H, Sandison, M E   +7 more
core   +2 more sources

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

Journal of Lipid Research, 2015
A Förster resonance energy transfer-based fusion and transfer assay was developed to study, in model membranes, protein-mediated membrane fusion and intermembrane lipid transfer of fluorescent sphingolipid analogs.
Günter Schwarzmann, Bernadette Breiden, Konrad Sandhoff   +2 more
doaj   +1 more source

Optical Switches for Lipid Membranes: Computed Molecular Projection Area as a Switch Selection Criterion

Colloids and Interfaces, 2022
Optical switches in lipid membranes are an emerging tool to tune the properties of the bilayer or membrane protein integrated therein. Here, we use simple geometry and physics considerations to deduce structural criteria to design efficient ...
Ivan Boldyrev
doaj   +1 more source

Stresses in lipid membranes [PDF]

Journal of Physics A: Mathematical and General, 2002
16 pages, introduction rewritten, other minor changes, new references added, version to appear in Journal of Physics ...
Capovilla, R., Guven, J.
openaire   +3 more sources