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FEBS Letters, 1974 Today, as in 1964, those who are concerned with membranes are broadly divided into two main groups: investigators who work on lipids and others who study proteins. Whether one pursues mainly this aspect or that is often more the result of individual interest and background rather than the outcome of a decision that one particular aspect of membranes is
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Lipidomics in research on yeast membrane lipid homeostasis [PDF]
, 2017 Mass spectrometry is increasingly used in research on membrane lipid homeostasis, both in analyses of the steady state lipidome at the level of molecular lipid species, and in pulse-chase approaches employing stable isotope-labeled lipid precursors ...
de Kroon, Anton I P M +2 more
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Special Issue on “Sphingolipids: From Pathology to Therapeutic Perspectives”
Cells, 2020 It is an honor for us to dedicate this Special Issue to our dearest friend Lina Obeid, who was not only a pioneer in the field of sphingolipids, but also a remarkable personality [...]
Gerhild van Echten-Deckert
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Journal of Lipid Research, 2019 The catabolism of ganglioside GM2 is dependent on three gene products. Mutations in any of these genes result in a different type of GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease, and the B1 and AB variants of GM2 gangliosidosis), with GM2 as ...
Susi Anheuser +2 more
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Life, 2021 With the aim of better understanding the nature of metabolism in the first cells and the relationship between the origin of life and the origin of metabolism, we propose three criteria that a chemical reaction system must satisfy in order to constitute a
Paul G. Higgs
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Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity[S]
Journal of Lipid Research, 2015 Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of SM and with cholesterol in type C.
Susi Anheuser +3 more
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Life, 2023 Lateral phase separation within lipid bilayer membranes has attracted considerable attention in the fields of biophysics and cell biology. Living cells organize laterally segregated compartments, such as raft domains in an ordered phase, and regulate ...
Naofumi Shimokawa, Tsutomu Hamada
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Spiroplasma membrane lipids [PDF]
Journal of Bacteriology, 1985 Membranes of six spiroplasma strains belonging to different Spiroplasma species and subgroups were isolated by a combination of osmotic lysis and sonication in the presence of EDTA to block endogenous phospholipase activity. Analysis of membrane lipids showed that in addition to free and esterified cholesterol the spiroplasmas incorporated exogenous ...
P J, Davis +3 more
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Journal of Lipid Research, 2014 Within recent years, ganglioside patterns have been increasingly analyzed by MS. However, internal standards for calibration are only available for gangliosides GM1, GM2, and GM3.
Martin Gantner +3 more
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Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase
Journal of Lipid Research, 2017 Glucosylceramide (GlcCer) is the primary storage lipid in the lysosomes of Gaucher patients and a secondary one in Niemann-Pick disease types A, B, and C.
Misbaudeen Abdul-Hammed +3 more
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