Results 71 to 80 of about 1,237,091 (306)
Editorial: Membrane lipids in T cell functions [PDF]
Plasma membrane lipids play essential roles in regulating T cell signaling, differentiation, and effector functions. The major lipid species in the plasma membrane are glycerophospholipids, sphingolipids, and sterol lipids.
Tuosto, Loretta, Xu, Chenqi
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers. [PDF]
A nanolipoprotein particle (NLP) is a lipid bilayer disc stabilized by two amphipathic "scaffold" apolipoproteins. It has been most notably utilized as a tool for solubilizing a variety of membrane proteins while preserving structural and functional ...
Coleman, Matthew A +4 more
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Effect of Counter Electrode in Electroformation of Giant Vesicles
Electroformation of cell-sized lipid membrane vesicles (giant vesicles, GVs), from egg yolk phosphatidylcholine, was examined varying the shape of the counter electrode.
Shuuhei Oana, Yukihisa Okumura
doaj +1 more source
Membrane Lipid Switches: How Membrane Lipid Structure Influences Protein–Lipid Interactions [PDF]
Peripheral membrane proteins are required for signal propagation upon ligand-induced receptor activation at the plasma membrane. The translocation of this amphitropic peripheral proteins from or to the plasma membrane enables signal cascade propagation into the cells.
Manuel Torres +4 more
openaire +1 more source
Tilt Texture Domains on a Membrane and Chirality induced Budding
We study the equilibrium conformations of a lipid domain on a planar fluid membrane where the domain is decorated by a vector field representing the tilt of the stiff fatty acid chains of the lipid molecules, while the surrounding membrane is fluid and ...
A. Radhakrishnan +20 more
core +2 more sources
μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]
μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Assfalg-Machleidt, Irmgard +5 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Lipid ion channels and the role of proteins [PDF]
Synthetic lipid membranes in the absence of proteins can display quantized conduction events for ions that are virtually indistinguishable from those of protein channel. By indistinguishable we mean that one cannot decide based on the current trace alone
Heimburg, Thomas, Mosgaard, Lars D.
core +1 more source

