Results 71 to 80 of about 847,311 (317)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Plasma membrane compartmentation in Saccharomyces cerevisiae
, 2009 In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core +1 more source
Effect of Counter Electrode in Electroformation of Giant Vesicles
Membranes, 2011 Electroformation of cell-sized lipid membrane vesicles (giant vesicles, GVs), from egg yolk phosphatidylcholine, was examined varying the shape of the counter electrode.
Shuuhei Oana, Yukihisa Okumura
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plantaricin NC8 from Lactobacillus plantarum causes cell membrane disruption to Micrococcus luteus without targeting lipid II [PDF]
, 2018 Plantaricin NC8, a two-peptide non-lantibiotic class IIb bacteriocin composed of PLNC8α and PLNC8β and derived from Lactobacillus plantarum ZJ316, has been shown to be highly potent against a range of bacteria and fungi.
Breukink, Eefjan +8 more
core +1 more source
Alteration of Average Thickness of Lipid Bilayer by Membrane-Deforming Inclusions
Biomolecules, 2023 Thickness of lipid bilayer membranes is a key physical parameter determining membrane permeability and stability with respect to formation of through pores.
Oleg V. Kondrashov, Sergey A. Akimov
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The interaction of amyloid-β peptide with lipid membranes and glycosaminoglycans [PDF]
, 2012 The aim of the thesis is a better understanding of the thermodynamics and structural aspects of the interaction of Aβ(1-40) with lipid membranes and glycosaminoglycans (GAGs).
Müller, Christian Thomas Benedikt
core +1 more source
Electrodiffusion of lipids on membrane surfaces [PDF]
The Journal of Chemical Physics, 2012 Lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when the random lateral motion is mediated by the electrostatic interactions and membrane curvature.
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source