Results 1 to 10 of about 2,639,820 (355)
Lipid metabolism reprogramming and its potential targets in cancer
Cancer Communications, 2018 Reprogramming of lipid metabolism is a newly recognized hallmark of malignancy. Increased lipid uptake, storage and lipogenesis occur in a variety of cancers and contribute to rapid tumor growth.
Chunming Cheng, Feng Geng, Xiang Cheng
exaly +2 more sources
Di-san junyi daxue xuebao, 2022 Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served
RAO Yuhan +4 more
doaj +1 more source
The FEBS Journal, 2022 Alzheimer’s disease (AD) is an age‐associated neurodegenerative disorder with multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of disease‐modifying therapeutics.
F. Yin
semanticscholar +1 more source
Molecular Neurodegeneration, 2022 Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane immune receptor that is mainly expressed on microglia in the brain and macrophages in the periphery.
Ruirui Li +8 more
semanticscholar +1 more source
Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases
Cell & Bioscience, 2022 The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by growing evidence in recent years.
Danying Yang +9 more
semanticscholar +1 more source
Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis
International Journal of Molecular Sciences, 2022 Regulated cell death (RCD) has a significant impact on development, tissue homeostasis, and the occurrence of various diseases. Among different forms of RCD, ferroptosis is considered as a type of reactive oxygen species (ROS)-dependent regulated ...
L. Rochette +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2020 Short-chain fatty acids (SCFAs), particularly acetate, propionate and butyrate, are mainly produced by anaerobic fermentation of gut microbes. SCFAs play an important role in regulating energy metabolism and energy supply, as well as maintaining the ...
Jin He +11 more
semanticscholar +1 more source
The interaction between ferroptosis and lipid metabolism in cancer
Signal Transduction and Targeted Therapy, 2020 Ferroptosis is a new form of programmed cell death characterized by the accumulation of iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that occur in lipid metabolism during ferroptosis and have provided intriguing ...
Dingshan Li, Yongsheng Li
semanticscholar +1 more source
Case Reports in Endocrinology, 2022 A 48-year-old man who was diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) due to a plakophilin 2 gene mutation developed acute both-sided heart failure with rapid atrial fibrillation and was hospitalized.
Masaki Matsubara +8 more
doaj +1 more source
Journal of Experimental Medicine, 2020 Dysregulation in lipid metabolism is among the most prominent metabolic alterations in cancer. This review discusses current knowledge about the advances in understanding lipid metabolism regulation in cancer cells and introduces therapies that disrupt ...
Xueli Bian +5 more
semanticscholar +1 more source