Results 91 to 100 of about 2,214,124 (236)

Natural Variation in GmSL20 Improves Seed Size and Quality in Soybean

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Seed size plays an important role in determining crop yield, yet the genetic mechanisms underlying the regulation of this agronomic trait remain incompletely understood in soybean. Here, we perform a genome‐wide association study mapping with seed length variations and identify a major quantitative trait locus (QTL) on chromosome 20, named ...
Yuechuan Luo   +12 more
wiley   +1 more source

Carnitine Inborn Errors of Metabolism

open access: yes, 2019
Carnitine plays essential roles in intermediary metabolism. In non-vegetarians, most of carnitine sources (~75%) are obtained from diet whereas endogenous synthesis accounts for around 25%.
Majid Alfadhel   +2 more
core   +1 more source

Inborn errors of metabolism in the differential diagnosis of fatty liver disease

open access: yes, 2020
Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease across all age groups. Obesity, diabetes, and metabolic syndrome, are the primary causes that are closely linked with the development of NAFLD.
YILDIZ, YILMAZ   +3 more
core   +1 more source

Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv   +11 more
wiley   +1 more source

Effects of Atmospheric CO2 Levels on the Susceptibility of Maize to Diverse Pathogens

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Rising atmospheric CO2 has significant implications for crop productivity and food security. Based on studies in C3 plants, elevated CO2 (eCO2) can shape plant‐pathogen interactions, although the outcomes are often variable. The question of how eCO2 influences immunity and disease development in C4 plants, such as the globally important cereal
Ekkachai Khwanbua   +5 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Inborn errors of pyrimidine metabolism: clinical update and therapy

open access: yes, 2014
Inborn errors involving enzymes essential for pyrimidine nucleotide metabolism have provided new insights into their fundamental physiological roles as vital constituents of nucleic acids as well as substrates of lipid and carbohydrate metabolism and in ...
Christodoulou, John   +2 more
core   +1 more source

Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study

open access: yes
British Journal of Haematology, EarlyView.
Maggie McNeill   +12 more
wiley   +1 more source

Oral health and systemic health outcomes: A call for interdisciplinary action

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives To make the case, from periodontology and dental public health, for interdisciplinary action on oral and systemic health, and to set out recommendations for practice, policy, education, and research. Materials and Methods A joint working group of the European Federation of Periodontology (EFP) and the European Association of Dental ...
Moritz Kebschull   +29 more
wiley   +1 more source

Progress toward improved therapies for inborn errors of metabolism

open access: yes, 2015
Because of their prevalence, severity and lack of effective treatments, inborn errors of metabolism need novel and more effective therapeutic approaches.
GINOCCHIO, virginia maria   +1 more
core   +1 more source

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