Results 71 to 80 of about 2,214,124 (236)
Neuroprotection, EarlyView.Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji +4 more
wiley +1 more source
Inherited disorders of complex lipid metabolism: A clinical review
, 2021 Over 80 human diseases have been attributed to defects in complex lipid metabolism. A majority of them have been reported recently in the setting of rapid advances in genomic technology and their increased use in clinical settings.
Ferreira, Carlos R. +3 more
core +1 more source
Pediatric Investigation, EarlyView.Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu +5 more
wiley +1 more source
Cardiovascular disease biomarkers in patients with inborn errors of protein metabolism: A pilot study [PDF]
, 2015 Background: Limited data exist so far on cardiovascular disease biomarkers in patients maintained on a protein-restricted diet for inborn errors of protein metabolism. The present study aimed to analyse plasma cholesterol, lipoproteins, triglycerides and
Daher, Rose T. +4 more
core +2 more sources
Occasional seizures, epilepsy, and inborn errors of metabolism
, 2014 Seizures are a common paediatric problem, with inborn errors of metabolism being a rare underlying aetiology. The clinical presentation of inborn errors of metabolism is often associated with other neurological symptoms, such as hypotonia, movement ...
Dulac, Olivier +7 more
core +1 more source
Special Issue on “Advances in Cholesterol and Lipid Metabolism”
, 2022 Cholesterol and lipid metabolism is a broad topic that encompasses multiple aspects of cellular function in every organ [...
Reiss, Allison B. +3 more
core +1 more source
Impact of sleep insufficiency and recovery on cancer development
Sleep Research, EarlyView.Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley +1 more source
Nutritional Management of Patients with Inborn Errors of Metabolism
Inborn errors of metabolism (IEM) are a large group of single-gene disorders resulting from enzyme defects in biochemical and metabolic pathways [...
Isidro Vitoria, María-Luz Couce
core +1 more source
Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
VIEW, EarlyView.Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source
EPILEPSY IN INBORN ERRORS OF METABOLISM [PDF]
, 2016 Epilepsy is a frequent and sometimes leading symptom in inborn errors of metabolism, especially in neonatal or infantile ones. Early myoclonic encephalopathy and myoclonus as a seizure type are the prototypes of epilepsy in inherited metabolic diseases ...
E. D. Belousova
core +1 more source