Results 11 to 20 of about 2,639,820 (355)
Advances in Understanding of the Role of Lipid Metabolism in Aging
Cells, 2021 During aging, body adiposity increases with changes in the metabolism of lipids and their metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity leads to various age-related diseases, including cardiovascular ...
K. Chung
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2014 Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs).
A. Ayala, Mario F. Muñoz, S. Argüelles
semanticscholar +1 more source
Contradictory roles of lipid metabolism in immune response within the tumor microenvironment
Journal of Hematology & Oncology, 2021 Complex interactions between the immune system and tumor cells exist throughout the initiation and development of cancer. Although the immune system eliminates malignantly transformed cells in the early stage, surviving tumor cells evade host immune ...
Weina Yu +7 more
semanticscholar +1 more source
Regulation of lipid metabolism by the unfolded protein response
Journal of Cellular and Molecular Medicine, 2021 The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca2+ storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca2+ homeostasis in the ER leads to the accumulation of unfolded proteins, a condition ...
Matthieu Moncan +5 more
semanticscholar +1 more source
Cardiovascular Diabetology, 2019 Background Visceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance.
Yoko Omura-Ohata +7 more
doaj +1 more source
The Effects of SGLT2 Inhibitors on Lipid Metabolism
Metabolites, 2021 Sodium glucose co-transporter 2 (SGLT2) inhibitors are effective antihyperglycemic agents by inhibiting glucose reabsorption in the proximal tubule of the kidney.
Zsolt Szekeres, K. Tóth, E. Szabados
semanticscholar +1 more source
New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages
Frontiers in Immunology, 2020 Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid biosynthesis.
A. Batista-González +3 more
semanticscholar +1 more source
Pediatric Discovery, 2023 A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
doaj +1 more source
Lipid Metabolism, Disorders and Therapeutic Drugs – Review
Biomolecules & Therapeutics, 2021 Different lifestyles have an impact on useful metabolic functions, causing disorders. Different lipids are involved in the metabolic functions that play various vital roles in the body, such as structural components, storage of energy, in signaling, as ...
V. Natesan, Sung-jin Kim
semanticscholar +1 more source
Lipid Metabolism and Ferroptosis
Biology, 2021 Simple Summary Ferroptosis is a type of cell death, which is morphologically and mechanistically distinct from other type of cell death pathways such as apoptosis and necroptosis.
Ji-Yoon Lee +4 more
semanticscholar +1 more source