Results 31 to 40 of about 3,175,424 (401)
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
, 2017 Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
core +3 more sources
Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows [PDF]
, 2015 Both high and low circulating urea concentrations, a product of protein metabolism, are associated with decreased fertility in dairy cows through poorly defined mechanisms.
Bekana +23 more
core +2 more sources
Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]
, 2015 Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core +1 more source
Gastroenterology, 2020 Changes in the intestinal microbiome have been associated with obesity and type 2 diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free mice.
J. Aron‐Wisnewsky +3 more
semanticscholar +1 more source
Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity [PDF]
, 2011 The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) enhances oxidative metabolism in skeletal muscle. Excessive lipid oxidation and electron transport chain activity can, however, lead to the accumulation of harmful metabolites and ...
Handschin, C. +3 more
core +1 more source
Pediatric Discovery, 2023 A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
doaj +1 more source
Lipid Metabolism, Disorders and Therapeutic Drugs – Review
Biomolecules & Therapeutics, 2021 Different lifestyles have an impact on useful metabolic functions, causing disorders. Different lipids are involved in the metabolic functions that play various vital roles in the body, such as structural components, storage of energy, in signaling, as ...
V. Natesan, Sung-jin Kim
semanticscholar +1 more source
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
, 2010 Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source
Regulation of Osteoclast Differentiation and Activity by Lipid Metabolism
Cells, 2021 Bone is a dynamic tissue and is constantly being remodeled by bone cells. Metabolic reprogramming plays a critical role in the activation of these bone cells and skeletal metabolism, which fulfills the energy demand for bone remodeling.
Haemin Kim +2 more
semanticscholar +1 more source
Lipids and lipid metabolism in the eye [PDF]
Journal of Lipid Research, 2009 The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
openaire +6 more sources