Results 31 to 40 of about 3,232,425 (402)

Advances in Understanding of the Role of Lipid Metabolism in Aging

Cells, 2021
During aging, body adiposity increases with changes in the metabolism of lipids and their metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity leads to various age-related diseases, including cardiovascular ...
K. Chung
semanticscholar   +1 more source

Nonimmunochemical quantitation of mammalian apolipoprotein A-I in whole serum or plasma by nonreducing gel electrophoresis.

Journal of Lipid Research, 1989
A rapid and convenient method for the quantitation of mammalian apoA-I has been developed. The method involves nonreducing sodium dodecyl sulfate gel electrophoresis and Coomassie blue staining, and takes advantage of the relative abundance of apoA-I in ...
D S France, T E Hughes, R Miserendino, J A Spirito, J Babiak, J B Eskesen, C Tapparelli, J R Paterniti, Jr   +7 more
doaj   +1 more source

Metabolism and Metabolic Disorders and the Microbiome: The intestinal microbiota associated with obesity, lipid metabolism and metabolic health: pathophysiology and therapeutic strategies.

Gastroenterology, 2020
Changes in the intestinal microbiome have been associated with obesity and type 2 diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free mice.
J. Aron‐Wisnewsky, Moritz V. Warmbrunn, M. Nieuwdorp, K. Clément   +3 more
semanticscholar   +1 more source

Regulation of lipid metabolism by the unfolded protein response

Journal of Cellular and Molecular Medicine, 2021
The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca2+ storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca2+ homeostasis in the ER leads to the accumulation of unfolded proteins, a condition ...
Matthieu Moncan, K. Mnich, A. Blomme, Aitor Almanza, Afshin Samali, A. Gorman   +5 more
semanticscholar   +1 more source

Hepatic phosphatidylcholines: evidence for synthesis in the rat by extensive reutilization of endogenous acylglycerides.

Journal of Lipid Research, 1994
Studies were performed to compare the extent of fatty acid incorporation into liver phosphatidylcholines (PCs) by acyl remodeling and by de novo synthesis.
G M Patton, J M Fasulo, S J Robins
doaj   +1 more source

The Effects of SGLT2 Inhibitors on Lipid Metabolism

Metabolites, 2021
Sodium glucose co-transporter 2 (SGLT2) inhibitors are effective antihyperglycemic agents by inhibiting glucose reabsorption in the proximal tubule of the kidney.
Zsolt Szekeres, K. Tóth, E. Szabados
semanticscholar   +1 more source

The association of soluble cluster of differentiation 36 with metabolic diseases: A potential biomarker and therapeutic target

Pediatric Discovery, 2023
A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
doaj   +1 more source

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud, Farese, Robert V, Harris, Charles, Herker, Eva, Hernandez, Céline, Kaehlcke, Katrin, Ott, Melanie, Rosenberg, Arielle R   +7 more
core   +1 more source

Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR (+/−) hamsters

Lipids in Health and Disease, 2021
Background Cordyceps militaris is cultured widely as an edible mushroom and accumulating evidence in mice have demonstrated that the polysaccharides of Cordyceps species have lipid-lowering effects.
Wen-Qian Yu, Fan Yin, Nuo Shen, Ping Lin, Bin Xia, Yan-Jie Li, Shou-Dong Guo   +6 more
doaj   +1 more source

Lipids and lipid metabolism in the eye [PDF]

Journal of Lipid Research, 2009
The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
openaire   +6 more sources