Results 221 to 230 of about 117,691 (310)

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Protocol for in vitro transfection of mRNA-encapsulated lipid nanoparticles. [PDF]

STAR Protoc
Youn K, Yoo S, Hwang IK, Gil H, Park H, Lee H, Oh S, Keum G, Bang EK.   +8 more
europepmc   +1 more source

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation

, 2018
Sebastián Scioli Montoto, María L. Sbaraglini, Alan Talevi, Manuel Couyoupetrou, Marta Ianni, Guido Pesce, Vera A. Álvarez, Luis E. Bruno‐Blanch, Guillermo R. Castro, María Esperanza Ruiz, Germán A. Islan   +10 more
openalex   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Loading of STING Agonist into Lipid Nanoparticles Boosts Dendritic Cell Activation. [PDF]

ACS Omega
Ribeiro AR, Eguskiza A, Dang HH, Neuper T, Unger MS, Rodriguez Comas L, Steiner M, Sieberer H, Zaborsky N, Greil R, Vilar I Hernandez M, Jonkheijm P, Fiammengo R, Horejs-Hoeck J.   +13 more
europepmc   +1 more source

Formulation And Characterization Of Solid Lipid Nanoparticles For The Treatment Of Skin Cancer

Bhaskar Sharma, Amit Bhargava
openalex   +2 more sources

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Construction of Spleen-Accumulated Polysorbate 20-Containing Ionizable Lipid Nanoparticles for mRNA Delivery. [PDF]

Nanomaterials (Basel)
Liu H, Li S, Chen K, Yao S, Tang X, Han X.   +5 more
europepmc   +1 more source

Exploring the landscape of Lipid Nanoparticles (LNPs): A comprehensive review of LNPs types and biological sources of lipids

Alanood S Alfutaimani, Nasibh Abdulrahman Alharbi, Amirah Alahmari, Almaha A Alqabbani, Abdulaziz M. Aldayel   +4 more
openalex   +1 more source