Results 61 to 70 of about 785,912 (313)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Steering Fatty Acid Composition of Yeast Microbial Oil via Genetic Modification and Bioprocess Adjustment

open access: yesFermentation
The increasing demand for palm oil has drastic effects on the ecosystem, as its production is not sustainable. To that end, developing a sustainable alternative to fatty acids and oils is urgent and of utmost interest.
Zeynep Efsun Duman-Özdamar   +5 more
doaj   +1 more source

Comparison between distinct insulin resistance indices in measuring the development of hypertension: The China Health and Nutrition Survey

open access: yesFrontiers in Cardiovascular Medicine, 2022
AimOur aim was to identify the relationship between several surrogate insulin resistance (IR) indices based on lipid products and the development of hypertension.Materials and methodsA total of 3,281 participants aged ≥ 18 years enrolled in the China ...
Yue Yuan   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Production of lipid from N-acetylglucosamine by Cryptococcus curvatus [PDF]

open access: yes, 2010
N-Acetylglucosamine (GlcNAc), the monomeric constituent of chitin, is rarely used as a carbon source for fermentation technology. In this study, we demonstrate that the oleaginous yeast Cryptococcus curvatus ATCC 20509 can produce intracellular lipid ...
Wu, Siguo   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Manipulation of lipid rafts in neuronal cells [PDF]

open access: yes, 2010
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core  

Effect of ultraviolet-B radiation on biomass production, lipid peroxidation, reactive oxygen species, and antioxidants in Withania somnifera [PDF]

open access: yes, 2014
The present study was aimed at understanding the effects of long term supplemental UV-B (3.6 kJ m-2 d-1) on biomass production, accumulation of reactive oxygen species, lipid peroxidation, and enzymatic antioxidants in leaves and roots of Withania ...
S. Takshak, S. B. Agrawal
core   +1 more source

Engineering of oleaginous organisms for lipid production [PDF]

open access: yesCurrent Opinion in Biotechnology, 2015
Phototrophs are attractive candidates for commercial lipid production. Lipid biosynthetic pathways in these organisms have been largely characterized but the mechanisms partitioning resources toward storage lipids are poorly understood. One promising strategy to study and enhance biomass lipid bioproduction in oleaginous microorganisms is to combine ...
Levering, Jennifer   +2 more
openaire   +2 more sources

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