Results 81 to 90 of about 782,035 (313)
Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers +9 morewiley +1 more sourceMicromachined glass apertures for artificial lipid bilayer formation in a microfluidic system [PDF]
, 1998 The use of spark assisted chemical engraving (SACE) to produce glass apertures that are suitable for the formation of artificial bilayer lipid membranes is described.Uttamchandani, D.G., Syms, R., Aljada, Muhsen, Yan Xing, Zhu, YH, Shi, XM, Ashok, A, Xing, Yan, Hida, Hirotaka, Shikida, M, Li, Yongyao, Pirri C, F., Ballestra, A., Lee, TMH, Pirri, Candido, Cai, H, Xing, Y, Blue, Robert, Gautam, A K, Weng, C, Brown, J.G., Zhang, Xin, Zhang, P., Xu, Y, DEZEST, D, Wong, Man, Kwan, FY, Sucher, Nikolaus J., Zeng, Fan, Pal, Prem, Agrawal, A, Svetovoy, Vitaly, Soma', Aurelio, Xiao, G, Qu, Xiaopeng, Sharma, V, Dong, Shu Rong, Yan, X, To, S, Dutta, A, Wai, PKA, Chu, HK, Y Xing, Song, Y. J., Chan, CY, Yue, TM, Ferrando, N, NICU, L, Gu, Changdong, Goslvez, M A, V Svetovoy, Karyn Mutkins, De Pasquale, Giorgio, Amit Agrawal, Shiv G Singh, Luo, Yuan, Wang, K, Duryodhan, V S, Fukuzawa, K, MATHIEU, Fabrice, Agrawal, Amit, Flockhart, Gordon M H, Chen, Xuyuan, Lo, GQ, Veijola, T., Jiang, Linan, THOMAS, Olivier, Tam, KF, Hida, H., Ehmann, KF, Gadea Gironés, Rafael, JASINEVICIUS, R. G., Zhang, Y, Song, Liyan, Zhang, X, Liu, H, Zagnoni, Michele, Kang, C, Canavese, Giancarlo, Cocuzza, Matteo, Liu, B, Cui, Jingzhi, Ko, SM, Krijnen, G.J.M.; id_orcid, Zhou, Jianying, Wong, Kam Sing, Mei, SM, Chen, R., Polido Gomes, J.F., Stagg, J., Marasso, Simone Luigi, VALES, L. F., Zhang, Tong Yi, Farinelli, P, de Bree, H.E., Zhu, Z, REMIENS, D, Hau, Winky L.W., Singh, Shiv Govind, Zhu, W, COSTECALDE, J, Yick Chuen Chan, Li, Li, Svetovoy, V.B., G J M Krijnen, Yang, W. W., Xu, Hui, Sandison, Mairi E., Hida, H, Zhang, SJ, B Tang, Cheng, Zaijun, Pan, W., Ferrando, Néstor, Chan, Mansun, Yung, KC, Xiao, K., M C Elwenspoek, CUNHA, L. S., N Ferrando, Lee, Yi Kuen, Yung, KL, BALLESTRA A., Chan, Yick Chuen, NICU, Liviu, Sharma, A K, COSTECALDE, Jean, Lee, Sylvanus Yuk Kwan, Lijie Li, M Shikida, Bhide, R R, J Cerdá, Giuri, E., Gosalvez Ayuso, Miguel Angel, Zagnoni, M., Trau, Dieter W., Tan, Q, Singh, S S, Wu, Zhangming, Shu, Yi, Prem Pal, Pandey, A K, Morgan, Hywel, H-e De Bree, Burn, Paul, Sridharan, A, H Hida, Singh, S G, Li, Y, Ricciardi, Carlo, SOYER, C, Sato, Kazuo, Zhao, T. S., Qiu, H. H., Zhangming Wu, Wright, Mike T., R Gadea, Sandison, M.E., Abu-Hantash, Mustafa, ANDREETA, M. R. B., Meredith, Paul, Pal, P, Bai, G, Zhang, XM, 伞海生, Liu, AQ, Jin, Baidong, Li, Lijie, Yu, MB, CARASCHI, L. C., Wang, Wentao, Samuel Cheng, George Vamvounis, Tagliaferro, Alberto, Vamvounis, George, Li, Juntao, Deladi, S., Haldar, S, Cheng, CH, Bhide, Rohit R, J W Van Honschoten, Krijnen, G.J.M., Robert Blue, Jin, Hao, Duttagupta, S P, Gosalvez, M A, Liu, Bo, van Honschoten, J.W., Wu, Zhang Ming, Ma, Wei, Miguel A Gosálvez, Kwong, DL, SINGH, SG, Pandey, Ashok Kumar, DEÜ, Jean-François, Li Li, A Sridharan, Abu-Hantash, M., Lowrie, C., Ma, Xianghong, E. GIURI, Elwenspoek, M.C., Xianghong Ma, Lina Stankovic, Morgan, H., Chi, Guanxin, Desmulliez, M.P.Y., Cerda, J, Sharma, Vandana, Begbie, M., Stankovic, Lina, Rohit R Bhide, Mutkins, Karyn, DEZEST, Denis, V B Svetovoy, Liang, Bing, Lee, WB, Li, L., M A Gosalvez, Gordon M H Flockhart, Shin, Dong Youn, Zheng, YP, Feng, Zhihong, Sato, K, Yuan Li, Demarchi, Danilo, Ren, Tian Ling, Wentao Wang, Stankovic, Vladimir, Qiu, Huihe, Wang, Zhenlong, Yao, J., MATHIEU, F, Deepak Uttamchandani, DEÜ, J F, Kazuo Sato, Liu, Yikun, Vladimir Stankovic, Cerdá Boluda, Joaquín, San, Haisheng, Yi-Kuen Lee, Elwenspoek, Michael Curt, BHIDE, RR, Muhsen Aljada, Perrone, Denis, MAZENQ, L, Giorcelli, Mauro, Shin, Dong-Youn, Paul Burn, Sato, K., Mike T Wright, Yobas, Levent, Gosálvez, M. A., Wu, Q. X., Cheng, S., Li, Gang, Tang, B, Wang, Yuelin, Gadea, R, Krijnen, Gijsbertus J.M., Xiaopeng Qu, Uttamchandani, Deepak, Sandison, M E, Weiland, D., Cheung, CF, Zhou, Changjian, Huihe Qiu, MAZENQ, Laurent, S Deladi, Veerla, S, Grassia, Paul, Sun, D, Ferrando Jódar, Néstor, Zohar, Yitshak, Wang, Rong Xin, Svetovoy, V., Singh, Shiv G, Amakawa, H, REMIENS, Denis, Quaglio, Marzia, Li, Yuan, SOYER, Caroline, Morgan, H, Zou, H., Sanginario, Alessandro, VEIJOLA T., Paul Meredith, K Sato, Yang, Yi +288 morecore +1 more sourceHippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà +11 morewiley +1 more sourceLipid production by Rhodosporidium toruloides Y4 using different substrate feeding strategies
, 2011 Lipid production by Rhodosporidium toruloides Y4 using different substrate feeding strategiesMicrobial lipid is a potential alternative feedstock for the biodiesel industry.Wu, Siguo, 赵宗保, Zhao, Xin, Shen, Hongwei, Zhao, Zongbao K., Hu, Cuimin +5 morecore +1 more sourceEfficient conversion of biomass into lipids by using the simultaneous saccharification and enhanced lipid production process [PDF]
, 2013 Background: Microbial lipid production by using lignocellulosic biomass as the feedstock holds a great promise for biodiesel production and biorefinery.Zhiwei Gong, 赵宗保, Shen, Hongwei, Gong, Zhiwei, Hongwei Shen, Xie, Haibo, Xiaobing Yang, Zongbao K Zhao, Shen,Hongwei, Xie,Haibo, Haibo Xie, Yang, Xiaobing, Wang,Qian, Wang, Qian, Zhao, Zongbao K., Gong,Zhiwei, Yang,Xiaobing, Zhao,Zongbao K, Qian Wang +18 morecore +1 more sourceInteraction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen +9 morewiley +1 more source