Results 91 to 100 of about 880,370 (262)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

BMI Modulates the Effect of Thyroid Hormone on Lipid Profile in Euthyroid Adults

International Journal of Endocrinology, 2017
The impacts of thyroid hormones (TH) on lipid profile in euthyroid adults have gained much attention. It is currently unknown whether BMI influences such interaction.
Yanqiu Wang, Qinglei Yin, Min Xu, Qicheng Ni, Weiqing Wang, Qidi Wang   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Lipid Profile levels on the second day of Acute Myocardial Infarction; is it the right time for estimation? [PDF]

, 2012
The main objective of this study is to note the changes that occur in the lipid profile levels following an acute myocardial ischemic attack and also correlate the changes in the lipid profile levels to the ischemic markers (Cardiac troponin-I and AST ...
Amar Nagesh Kumar, Rama Krishna Reddy, Sushma Reddy   +2 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Correlations between anthropometry and lipid profile in women with PCOS

Journal of Human Reproductive Sciences, 2017
Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in reproductive age women and is associated with both reproductive and metabolic abnormalities. Recent studies have demonstrated an early onset of abnormal cardiovascular risk
Donthu Kiranmayee, Kothapalli Kavya, Yalamanchali Himabindu, Manne Sriharibabu, Gadi Leela Jaya Madhuri, Swargam Venu   +5 more
doaj   +1 more source

Changes in body composition and fatty acid profile during embryogenesis of quillback rockfish (Sebastes maliger) [PDF]

, 2009
We investigated developmental changes in the body compositions and fatty acid (FA) profiles of embryos and preparturition larvae of the quillback rockfish (Sebastes maliger).
Rodgveller, Cara A., Sewall, Fletcher F.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Traditional lipid profile and underdiagnosis of chronic complications in diabetic population in Nigeria [PDF]

Al Ameen Journal of Medical Sciences, 2019
Background: Traditional lipid profile is widely used in cardiovascular risk assessment in most of the health care centers despite the shortfall in its sensitivity to cardiovascular disease risk and clinical disease which had led to efforts to improve its
Blessing K. Myke-Mbata, Samuel C. Meludu, Chudi. E. Dioka, Izuchukwu N. Mba   +3 more
doaj  

Lipid profile changes before and after treatment in patients with bipolar disorder manic episode

Psychiatry and Clinical Psychopharmacology, 2021
Objective: In this study, we aimed to evaluate the changes in lipid profile before and after the treatment in patients suffering bipolar disorder, who were in manic episode. Method: In this study, we included inpatients with bipolar disorder (BD), who
Tevfik Kalelioğlu, Abdullah Genç, Akif Taşdemir, Ferda Can Güngör, Nesrin Karamustafalıoğlu, Murat Emül, Özlem Tanrıöver, Mehmet Cem İlnem   +7 more
doaj