Results 71 to 80 of about 880,370 (262)
Serum Lipid Profile And Random Blood Glucose of Male And Female Wistar Rats Following Administration of Leptin Hormone After A Dietary Regime [PDF]
, 2016 The Leptin hormone is a product of the obesity gene, a key regulator of feeding and energy expenditure.The World Health Organization (WHO) predicts 11.1 million deaths globally and 71% deaths in developing countries due to Coronary Artery Disease (CAD ...
G, E. U. (Egesie) +3 more
core
Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [PDF]
, 2019 Confocal Raman microscopy has a number of advantages in investigating the human stratum corneum (SC) in vivo and ex vivo. The penetration profiles of xenobiotics in the SC, as well as depth profiles of the physiological parameters of the SC, such as the ...
Choe, Chun-Sik +3 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Lipoprotein particles in patients with pediatric Cushing disease and possible cardiovascular risks. [PDF]
, 2019 BackgroundCardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD.
Belyavskaya, Elena +10 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Lipids in Health and DiseaseBackground Dyslipidemia is a key contributor to atherosclerotic cardiovascular disease (ASCVD). Despite the well-established correlation between abnormal lipid metabolism and ASCVD, existing diagnostic and predictive models based on lipid indices alone ...
Hongli Wan +4 more
doaj +1 more source
Inclusions induced phase separation in mixed lipid film
, 1999 The effect of rigid inclusions on the phase behavior of a film containing a mixture of lipid molecules is investigated. In the proposed model, the inclusion-induced deformation of the film, and the resulting energy cost are strongly dependent upon the ...
Safran, S., Sens, P.
core +3 more sources
Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]
, 1989 Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter +1 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source