Results 111 to 120 of about 1,129,041 (391)

Endothelium in spots--high-content imaging of lipid rafts clusters in db/db mice. [PDF]

PLoS ONE, 2014
Lipid rafts (LRs) are dynamic, sterol- and sphingolipid-enriched nanodomains involved in the regulation of cellular functions and signal transduction, that upon stimuli, via (e.g.
Marta Pilarczyk, Lukasz Mateuszuk, Anna Rygula, Mariusz Kepczynski, Stefan Chlopicki, Malgorzata Baranska, Agnieszka Kaczor   +6 more
doaj   +1 more source

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity [PDF]

, 2009
L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role in the progression of human carcinoma. Overexpression promotes tumour-cell invasion and motility, growth in nude mice and tumour metastasis.
Altevogt, Peter, Bondong, Sandra, Gast, Daniela, Gutwein, Paul, Kiefel, Helena, Riedle, Svenja, Wolterink, Silke   +6 more
core  

Domain Growth Kinetics in a Cell-sized Liposome [PDF]

, 2005
We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump.
Bagatolli L. A., Baumgart T., Brown D. A., Furukawa H., Hamada T., Imai M., Karatekin E., Komura S., Korlach J., Kusumi A., Laradji M., Lipowsky R., McConnell H. M., Momura S. M., Noireaux V., Ohki K., Roux A., Saffman P. G., Seul M., Silvius J. R., Simons K., Taniguchi T., Veatch S. L., Veatch S. L., Veatch S. L., Veatch S. L., Yamashita Y., Yu W.   +27 more
core   +3 more sources

Anesthetics interacting with lipid rafts

European Journal of Pharmaceutical Sciences, 2013
The exact mechanism by which anesthetics induce cell membrane-mediated modifications is still an open question. Although the fluidization effect of the anesthetic molecules on the cellular membrane is widely recognized, it is not known if anesthetics show any preference for specific membrane domains, namely the lipid rafts.
Catia Bandeiras, Konstantin V. Luzyanin, Konstantin V. Luzyanin, Anabela C. Fernandes, Benilde Saramago, Ana Paula Serro, Ana Paula Serro   +6 more
openaire   +3 more sources

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir, Banning, Antje, Eming, Rüdiger, Exner, Yvonne, Hertl, Michael, Kurrle, Nina, Tikkanen, Ritva, Völlner, Frauke   +7 more
core   +1 more source

Caveosomes and endocytosis of lipid rafts [PDF]

Journal of Cell Science, 2003
Endocytosis of various endogenous plasma membrane molecules, including signalling receptors, glycosphingolipids and glycosylphosphatidylinositol (GPI)-linked proteins, occurs in the absence of functional clathrin-coated pits. Most of these molecules are found in biochemically defined lipid rafts, which suggests that at least some clathrin-independent ...
openaire   +2 more sources

Lipid raft heterogeneity: an enigma [PDF]

Journal of Neurochemistry, 2007
AbstractGlycosphingolipids (GSLs) and glycoproteins are ubiquitous components of mammalian cell membranes. GSLs are especially enriched in the nervous system and significantly contribute to membrane organization and a variety of cellular functions. Current body of evidence suggests that GSLs along with cholesterol are enriched in discrete membrane ...
Preeti G. Joshi, Sudha Mishra
openaire   +3 more sources

Live Quantitative Characterization for Stem Cell Biomechanics

Advanced Materials Interfaces, EarlyView.
These findings demonstrate an accessible technique for real‐time, high‐resolution mechanical mapping of live stem cells, without the use of specialised probes or advanced modelling techniques. This approach provides direct insight into localised cytoskeletal dynamics under chemical treatment and holds potential for broader application in understanding ...
Kaiwen Zhang, Chayla L. Reeves, Joseph D. Berry, Kate E. Fox, Aaron Elbourne, Amy Gelmi   +5 more
wiley   +1 more source

Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts.

PLoS Pathogens, 2013
Lipid rafts in eukaryotic cells are sphingolipid and cholesterol-rich, ordered membrane regions that have been postulated to play roles in many membrane functions, including infection.
Timothy J LaRocca, Priyadarshini Pathak, Salvatore Chiantia, Alvaro Toledo, John R Silvius, Jorge L Benach, Erwin London   +6 more
doaj   +1 more source