Results 31 to 40 of about 3,299,584 (293)
Transport of lipids in insects
Many insect species are almost completely dependent on lipids for their metabolic needs, although this is usually a function of developmental stage. The primary storage organ is the fat body, which can constitute 50% of the fresh weight of the insect and also acts as the major metabolic center (analogous to the vertebrate adipose tissue and liver ...
Lawrence I. Gilbert, Haruo Chino
openaire +3 more sources
Valproic acid (VPA) is a fatty acid with strong anticonvulsant properties has different effects in different tissues with opposing mechanisms of action.
Domagoj Đikić +2 more
doaj +1 more source
Exchange of water for sterol underlies sterol egress from a StARkin domain
Previously we identified Lam/GramD1 proteins, a family of endoplasmic reticulum membrane proteins with sterol-binding StARkin domains that are implicated in intracellular sterol homeostasis. Here, we show how these proteins exchange sterol molecules with
George Khelashvili +4 more
doaj +1 more source
The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Periasamy Selvaraj +2 more
core +1 more source
MmpL Proteins in Physiology and Pathogenesis of M. tuberculosis
Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity.
Geoff Melly, Georgiana E. Purdy
doaj +1 more source
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles ...
Yan Zhen, Harald Stenmark
doaj +1 more source
Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells
Lipid oxidation is now thought to be an initiating and sustaining event in atherogenesis. Oxidatively fragmented phospholipids, namely 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC) and 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3 ...
Alexandra Moumtzi +5 more
doaj +1 more source
Transport outlook 2010: The potential for innovation [PDF]
This paper provides evidence on and discussion of recent developments in global transport markets and analyzes what policies look most promising for stabilizing CO2-emissions from light-duty vehicles.
International Transport Forum, OECD
core +1 more source
NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains
Intestinal cholesterol absorption is a key regulator of systemic cholesterol homeostasis. Excessive dietary cholesterol and its intestinal uptake lead to hypercholesterolemia, a major risk factor for cardiovascular disease.
Wataru Nihei +12 more
doaj +1 more source
Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism
Disorders of lipid and lipoprotein metabolism and transport are responsible for the development of a large spectrum of pathologies, ranging from cardiovascular diseases, to metabolic syndrome, even to tumour development.
Davide Gnocchi +3 more
doaj +1 more source

