Results 91 to 100 of about 15,145 (296)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Microbiote intestinal et lipides : impact sur la santé humaine [PDF]

open access: yes, 2014
Chez l’homme, plusieurs grammes de lipides atteignent chaque jour le côlon où ils se retrouvent en contact avec le microbiote intestinal. Ces lipides sont alors capables de modifier la composition du microbiote qui, en retour, peut métaboliser une partie
Gerard, Philippe
core  

Détection oro-sensorielle des lipides alimentaires : Impacts sur le comportement alimentaire et la santé [PDF]

open access: yes, 2010
Colloque du 9 novembre 2010 : Les lipides: enjeux sensoriels et nutritionelsNational audienceFor the first time in its history, much of the world's population no longer has to "run after calories." An abundance of food has obvious consequences: it ...
Passilly-Degrace, Patricia   +3 more
core   +1 more source

Blunted orosensory perception of lipids during obesity: myth or reality?

open access: yesOilseeds and fats, crops and lipids
Obesity is now considered as a disease requiring treatment and prevention efforts by reason of severe associated co-morbidities and its growing prevalence in worldwide population.
Bernard Arnaud, Besnard Philippe
doaj   +1 more source

The products of peroxide lipids oxidations and bioantioxidants – glutathione and ascorbic acid of galophytes Salsola soda L., Glaucium flavum Crambs. and Euphorbia peplus L.

open access: yesІнтродукція Рослин, 2012
Process intensity of lipides peroxidation and bioantioxidants – glutathicone and different forms of ascorbic acid content in galophytes we analyzed Salsola soda L., Glaucium flavum Crambs. and Euphorbia peplus L. were studied.
I.V. Kosakivska   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Les lipides pour les seniors : besoins, alimentation et physiopathologie [PDF]

open access: yes, 2019
International audienceComme chaque année, le Groupe Lipides et Nutrition a choisi un thème d’actualité pour sa journée scientifique. Pour son édition 2018, celui du vieillissement a été retenu.
Jean-Michel Chardigny   +1 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy